Gastroesophageal reflux disease (GORD) affects up to 20% of Western populations, yet
sensory mechanisms underlying heartburn pathogenesis remain incompletely understood …

Background & Aims Mediators released by the intestinal mucosa of patients with irritable
bowel syndrome (IBS) affect the function of enteric and extrinsic sensory nerves, which can …

Ewing sarcoma (EWS) is an aggressive bone tumor of uncertain cellular origin. CD99 is a
membrane protein that is expressed in most cases of EWS, although its function in the …

Neuroblastoma is the most common extracranial solid tumor of childhood. One important
factor that predicts a favorable prognosis is the robust expression of the TRKA and p75NTR …

Irritable bowel syndrome (IBS) is the functional gastrointestinal disorder, characterized by
abdominal pain and altered bowel habits. The interest in intestinal immune activation as a …

Most of the previous work on the sphingolipid ceramide has been devoted to its function as
an apoptosis inducer. Recent studies, however, have shown that in stem cells, ceramide has …

Background Altered visceral sensation is common in irritable bowel syndrome (IBS) and
nerve growth factor (NGF) participates in visceral pain development. Sodium butyrate (NaB) …

The combined approach of mesenchymal stem cells (MSCs) and scaffolds has been
proposed as a potential therapeutic tool for the treatment of neurodegenerative diseases …

Brain development and learning is accompanied by morphological and molecular changes
in neurons. The growth associated protein 43 (Gap43), indicator of neurite elongation and …

Posttranscriptional regulation of gene expression by mRNA-binding proteins is critical for
neuronal development and function. hnRNP-Q1 is an mRNA-binding protein that regulates …