Worsening Heart Failure: Nomenclature, Epidemiology, and Future Directions: JACC Review Topic of the Week

SJ Greene, J Bauersachs, JJ Brugts… - Journal of the American …, 2023 - jacc.org
Heart failure (HF) is a progressive disease characterized by variable durations of
symptomatic stability often punctuated by episodes of worsening despite continued therapy …

Worsening of chronic heart failure: definition, epidemiology, management and prevention. A clinical consensus statement by the Heart Failure Association of the …

M Metra, D Tomasoni, M Adamo… - European Journal of …, 2023 - Wiley Online Library
Episodes of worsening symptoms and signs characterize the clinical course of patients with
chronic heart failure (HF). These events are associated with poorer quality of life, increased …

The different risk of new‐onset, chronic, worsening, and advanced heart failure: A systematic review and meta‐regression analysis

A Shakoor, S Abou Kamar, J Malgie… - European Journal of …, 2024 - Wiley Online Library
Aims Heart failure (HF) is a chronic and progressive syndrome associated with a poor
prognosis. While it may seem intuitive that the risk of adverse outcomes varies across the …

Outpatient worsening among patients with mildly reduced and preserved ejection fraction heart failure in the DELIVER trial

S Chatur, M Vaduganathan, BL Claggett… - Circulation, 2023 - Am Heart Assoc
BACKGROUND: Hospitalization is recognized as a sentinel event in the disease trajectory of
patients with heart failure (HF), but not all patients experiencing clinical decompensation are …

Worsening heart failure episodes outside a hospital setting in heart failure with preserved ejection fraction: the PARAGON-HF trial

M Vaduganathan, JW Cunningham, BL Claggett… - Heart Failure, 2021 - jacc.org
Objectives This study sought to evaluate the frequency and prognostic implications of urgent
heart failure (HF) visits in a large global clinical trial of HF with preserved ejection fraction …

Building a heart failure clinic: a practical guide from the Heart Failure Society of America

SJ Greene, S Adusumalli, NM Albert… - Journal of Cardiac …, 2021 - Elsevier
Heart failure (HF) remains a leading cause of mortality and morbidity and a primary driver of
health care resource use in the United States. As such, there continues to be much interest …

Practical outpatient management of worsening chronic heart failure

N Girerd, N Mewton, J Tartière… - European Journal of …, 2022 - Wiley Online Library
Management of worsening heart failure (WHF) has traditionally been hospital‐based, but
with the rising burden of heart failure (HF), the pressure on healthcare systems exerted by …

Diuretic changes, health care resource utilization, and clinical outcomes for heart failure with reduced ejection fraction: from the Change the Management of Patients …

MS Khan, SJ Greene, AS Hellkamp… - Circulation: Heart …, 2021 - Am Heart Assoc
Background: Diuretics are a mainstay therapy for the symptomatic treatment of heart failure.
However, in contemporary US outpatient practice, the degree to which diuretic dosing …

Importance of diagnostic setting in determining mortality in patients with new-onset heart failure: temporal trends in Denmark from 1997 to 2017

A Arulmurugananthavadivel, A Holt… - … Journal-Quality of …, 2022 - academic.oup.com
Aim To investigate temporal trends in inpatient vs. outpatient diagnosis of new-onset heart
failure (HF) and the subsequent risk of death and hospitalization. Methods and results Using …

Semaglutide and Diuretic Use in Obesity-Related Heart Failure with Preserved Ejection Fraction: A Pooled Analysis of the STEP-HFpEF and STEP-HFpEF-DM trials

SJ Shah, K Sharma, BA Borlaug, J Butler… - European Heart …, 2024 - academic.oup.com
Abstract Background and Aims In the STEP-HFpEF trial program, treatment with semaglutide
resulted in multiple beneficial effects in patients with obesity-related heart failure with …