The mouse brain is the most extensively studied brain of all species. We performed an
exhaustive review of the literature to establish our current state of knowledge on cell …

Neocortical areas are believed to be organized into vertical modules, the cortical columns,
and the horizontal layers 1–6. In the somatosensory barrel cortex these columns are defined …

We present a first-draft digital reconstruction of the microcircuitry of somatosensory cortex of
juvenile rat. The reconstruction uses cellular and synaptic organizing principles to …

INTRODUCTION The brain of mammals consists of an enormously dense network of
neuronal wires: the axons and dendrites of nerve cells. Their packing density is so high that …

In the rodent vibrissal system, active sensation and sensorimotor integration are mediated in
part by connections between barrel cortex and vibrissal motor cortex. Little is known about …

Understanding how brain activation mediates behaviors is a central goal of systems
neuroscience. Here, we apply an automated method for mapping brain activation in the …

Neurodevelopmental disorders (NDDs), including intellectual disability (ID) and autism
spectrum disorders (ASD), are a large group of disorders in which early insults during brain …

Soma location, dendrite morphology, and synaptic innervation may represent key
determinants of functional responses of individual neurons, such as sensory-evoked spiking …

Understanding the mechanisms of perception, cognition, and behavior requires instruments
that are capable of recording and controlling the electrical activity of many neurons …

The deepest layer of the cortex (layer 6b [L6b]) contains relatively few neurons, but it is the
only cortical layer responsive to the potent wake-promoting neuropeptide orexin/hypocretin …