Cross-domain and viral interactions in the microbiome

AD Rowan-Nash, BJ Korry, E Mylonakis… - … and Molecular Biology …, 2019 - Am Soc Microbiol
The importance of the microbiome to human health is increasingly recognized and has
become a major focus of recent research. However, much of the work has focused on a few …

Parasite-microbiota interactions with the vertebrate gut: synthesis through an ecological lens

JM Leung, AL Graham, SCL Knowles - Frontiers in microbiology, 2018 - frontiersin.org
The vertebrate gut teems with a large, diverse, and dynamic bacterial community that has
pervasive effects on gut physiology, metabolism, and immunity. Under natural conditions …

Detection of succinate by intestinal tuft cells triggers a type 2 innate immune circuit

MS Nadjsombati, JW McGinty, MR Lyons-Cohen… - Immunity, 2018 - cell.com
In the small intestine, type 2 responses are regulated by a signaling circuit that involves tuft
cells and group 2 innate lymphoid cells (ILC2s). Here, we identified the microbial metabolite …

Infection by the parasitic helminth Trichinella spiralis activates a Tas2r-mediated signaling pathway in intestinal tuft cells

XC Luo, ZH Chen, JB Xue, DX Zhao… - Proceedings of the …, 2019 - National Acad Sciences
The parasitic helminth Trichinella spiralis, which poses a serious health risk to animals and
humans, can be found worldwide. Recent findings indicate that a rare type of gut epithelial …

Factors influencing equine gut microbiota: Current knowledge

A Garber, P Hastie, JA Murray - Journal of Equine Veterinary Science, 2020 - Elsevier
Gastrointestinal microbiota play a crucial role in nutrient digestion, maintaining animal
health and welfare. Various factors may affect microbial balance often leading to …

[HTML][HTML] The impact of a helminth-modified microbiome on host immunity

TP Brosschot, LA Reynolds - Mucosal immunology, 2018 - Elsevier
Intestinal helminths have well-characterized modulatory effects on mammalian immune
pathways. Ongoing helminth infection has been associated with both the suppression of …

Oral antibiotic treatment of mice exacerbates the disease severity of multiple flavivirus infections

LB Thackray, SA Handley, MJ Gorman, S Poddar… - Cell reports, 2018 - cell.com
Although the outcome of flavivirus infection can vary from asymptomatic to lethal,
environmental factors modulating disease severity are poorly defined. Here, we observed …

The influence of the microbiome on allergic sensitization to food

CH Plunkett, CR Nagler - The Journal of Immunology, 2017 - journals.aai.org
The alarming increase in the incidence and severity of food allergies has coincided with
lifestyle changes in Western societies, such as dietary modifications and increased antibiotic …

Helminths and bacterial microbiota: The interactions of two of humans'“old friends”

K Llinás-Caballero, L Caraballo - International Journal of Molecular …, 2022 - mdpi.com
Humans have coexisted with helminths and bacteria for the entire existence of our species.
Nowadays, helminth infections affect more than 1.9 billion people worldwide, especially in …

This gut ain't big enough for both of us. Or is it? Helminth–microbiota interactions in veterinary species

LE Peachey, TP Jenkins, C Cantacessi - Trends in parasitology, 2017 - cell.com
Gastrointestinal helminth parasites share their habitat with a myriad of other organisms, that
is, the commensal microbiota. Increasing evidence, particularly in humans and rodent …