The role of tissue engineering in articular cartilage repair and regeneration

L Zhang, J Hu, KA Athanasiou - Critical Reviews™ in …, 2009 - dl.begellhouse.com
Articular cartilage repair and regeneration continue to be largely intractable because of the
poor regenerative properties of this tissue. The field of articular cartilage tissue engineering …

Recent progress in interfacial tissue engineering approaches for osteochondral defects

NJ Castro, SA Hacking, LG Zhang - Annals of biomedical engineering, 2012 - Springer
This review provides a brief synopsis of the anatomy and physiology of the osteochondral
interface, scaffold-based and non-scaffold based approaches for engineering both tissues …

Arginine-glycine-aspartic acid modified rosette nanotube–hydrogel composites for bone tissue engineering

L Zhang, F Rakotondradany, AJ Myles, H Fenniri… - Biomaterials, 2009 - Elsevier
An RGDSK (Arg-Gly-Asp-Ser-Lys) modified rosette nanotube (RNT) hydrogel composite with
unique surface chemistry and favorable cytocompatibility properties for bone repair was …

Engineering a biomimetic three-dimensional nanostructured bone model for breast cancer bone metastasis study

W Zhu, M Wang, Y Fu, NJ Castro, SW Fu, LG Zhang - Acta biomaterialia, 2015 - Elsevier
Traditional breast cancer (BrCa) bone metastasis models contain many limitations with
regards to controllability, reproducibility and flexibility of design. In this study, a novel …

Biologically inspired rosette nanotubes and nanocrystalline hydroxyapatite hydrogel nanocomposites as improved bone substitutes

L Zhang, J Rodriguez, J Raez, AJ Myles… - …, 2009 - iopscience.iop.org
Today, bone diseases such as bone fractures, osteoporosis and bone cancer represent a
common and significant public health problem. The design of biomimetic bone tissue …

Tuning cell adhesion on titanium with osteogenic rosette nanotubes

L Zhang, UD Hemraz, H Fenniri… - Journal of biomedical …, 2010 - Wiley Online Library
Self‐assembled rosette nanotubes (RNTs), obtained from a twin G∧ C base functionalized
with lysine‐arginine‐serine‐arginine [KRSR–(G∧ C) 2], were designed and investigated as …

[HTML][HTML] Method for in vitro production of cartilage microtissues from scaffold-free spheroids composed of human adipose-derived stem cells

VTK Tu, HTN Le, XHV To… - Biomedical …, 2020 - bmrat.biomedpress.org
Introduction: Cartilage damage is one of the injuries that is difficult for the human body to self-
repair due to the avascular and completely mature tissue with only few stem or progenitor …

Enhanced human bone marrow mesenchymal stem cell functions on cathodic arc plasma-treated titanium

W Zhu, G Teel, CM O'Brien, T Zhuang… - International Journal …, 2015 - Taylor & Francis
Surface modification of titanium for use in orthopedics has been explored for years;
however, an ideal method of integrating titanium with native bone is still required to this day …

Drug nanocrystals: Present, past and future

AR Fernandes, J Dias-Ferreira… - … materials in drug …, 2018 - Elsevier
Nanocrystals belong to a new type of drug delivery system, consisting of a pure drug with a
mean size between 100 nm and 400 nm, which has been developed to improve the …

Biomimetic biphasic 3D nanocomposite scaffold for osteochondral regeneration

NJ Castro, CM O'brien, LG Zhang - US Patent 10,406,261, 2019 - Google Patents
The invention describes methods for producing a biphasic nanocomposite scaffold
comprising custom polymer-based core-shelled nanospheres by the physical and chemical …