Increasing litter size has long been a goal of pig breeders and producers, and may have
implications for pig (Sus scrofa domesticus) welfare. This paper reviews the scientific …

Epidemiology formed the basis of 'the Barker hypothesis', the concept of 'developmental
programming'and today's discipline of the Developmental Origins of Health and Disease …

Background Nephron number is a major determinant of long-term renal function and
cardiovascular risk. Observational studies suggest that maternal nutritional and metabolic …

Purpose The theory of the developmental origins of health and disease hypothesizes that
low birth weight (≤ 5.5 lb) indicative of poor fetal growth is associated with an increased risk …

It is well established that altered maternal nutrition may induce long-term metabolic
consequences in offspring. However, the effects of maternal undernutrition during different …

A systematic review of the literature was performed in July 2011. Original papers based on
longitudinal studies measuring spine, femoral neck, or total body bone mass by DXA were …

The objective of this study was to examine the effect of embryonic nutritional enrichment on
the development and properties of broiler leg bones (tibia and femur) from the prenatal …

METHODS: Women were randomized to a single dose of betamethasone or placebo,≥ 7
days after an initial course of glucocorticoids, repeated each week that they remained at risk …

Introduction Low birthweight is associated with diseases later in life. The mechanisms for
these associations are not well known. If the hypothesis concerning “maternal constraint” is …

Intrauterine growth restriction (IUGR) is a major cause of antenatal brain injury. We aimed to
characterize cerebellar deficits following IUGR and to investigate the potential underlying …