Background Although non-alcoholic fatty liver disease (NAFLD) is commonly associated
with obesity, it is increasingly being identified in non-obese individuals. We aimed to …

Gut microbiota dysbiosis has been repeatedly observed in obesity and type 2 diabetes
mellitus, two metabolic diseases strongly intertwined with non-alcoholic fatty liver disease …

This update of evidence-based guidelines (GL) aims to translate current evidence and
expert opinion into recommendations for multidisciplinary teams responsible for the optimal …

Nonalcoholic fatty liver disease (NAFLD) spans steatosis through nonalcoholic
steatohepatis, cirrhosis, and hepatocellular carcinoma (HCC) associated with striking …

The importance of metabolic syndrome (MetS) lies in its associated risk of cardiovascular
disease and type 2 diabetes, as well as other harmful conditions such as nonalcoholic fatty …

Choline, an essential dietary nutrient for humans, is required for the synthesis of the
neurotransmitter, acetylcholine, the methyl group donor, betaine, and phospholipids; and …

Background The association between obesity and nonalcoholic fatty liver disease (NAFLD)
has not been fully quantified, and the magnitude of NAFLD risk associated with obesity is …

Many studies suggest that trimethylamine-N-oxide (TMAO), a gut-flora-dependent metabolite
of choline, contributes to the risk of cardiovascular diseases, but little is known for non …

Choline is a water-soluble nutrient essential for human life. Gut microbial metabolism of
choline results in the production of trimethylamine (TMA), which, upon absorption by the host …

Non-alcoholic fatty liver disease (NAFLD) is a chronic liver disorder closely linked to obesity,
hyperlipidemia and type 2 diabetes and is increasingly recognized as a major health …