Advances in Hybrid Polymer‐Based Materials for Sustained Drug Release

LNM Ribeiro, ACS Alcântara… - … Journal of Polymer …, 2017 - Wiley Online Library
The use of biomaterials composed of organic pristine components has been successfully
described in several purposes, such as tissue engineering and drug delivery. Drug delivery …

Enhancing topical analgesic administration: review and prospect for transdermal and transbuccal drug delivery systems

R Sanz, A C. Calpena, M Mallandrich… - Current …, 2015 - benthamdirect.com
Topical administration is an appealing method for drug delivery due to its non-invasiveness,
selfcontrolled application, avoidance of first-pass metabolism in the liver and reduction of …

Modified glutinous rice starch-chitosan composite films for buccal delivery of hydrophilic drug

MT Soe, T Pongjanyakul, E Limpongsa… - Carbohydrate …, 2020 - Elsevier
The fabrication and characterization of ball-milling modified glutinous rice starch (MGRS):
chitosan (CS) composite films were demonstrated. Effect of CS ratios (2: 1, 1: 1, 1: 2 MGRS …

Liposomal lidocaine gel for topical use at the oral mucosa: characterization, in vitro assays and in vivo anesthetic efficacy in humans

M Franz-Montan, D Baroni, G Brunetto… - Journal of liposome …, 2015 - Taylor & Francis
Objective: To characterize liposomal-lidocaine formulations for topical use on oral mucosa
and to compare their in vitro permeation and in vivo anesthetic efficacy with commercially …

Hybrid hydrogel composed of polymeric nanocapsules co-loading lidocaine and prilocaine for topical intraoral anesthesia

BV Muniz, D Baratelli, S Di Carla, L Serpe… - Scientific Reports, 2018 - nature.com
This study reports the development of nanostructured hydrogels for the sustained release of
the eutectic mixture of lidocaine and prilocaine (both at 2.5%) for intraoral topical use. The …

Mucoadhesive liquid crystal precursor system for photodynamic therapy of oral cancer mediated by methylene blue

GMFC Balian, MT Luiz, LD Di Filippo… - … and Photodynamic Therapy, 2023 - Elsevier
Oral cancer is one of the most prevalent types of cancer head and neck cancers worldwide.
Photodynamic therapy (PDT) has demonstrated great potential against cancers, reducing …

Evaluation of different pig oral mucosa sites as permeability barrier models for drug permeation studies

M Franz-Montan, L Serpe, CCM Martinelli… - European Journal of …, 2016 - Elsevier
The objective of the present study was to investigate the influence of preparation and
storage conditions on the histology and permeability of different parts of porcine oral mucosa …

Influence of salivary washout on drug delivery to the oral cavity using coated microneedles: An in vitro evaluation

L Serpe, A Jain, CG de Macedo, MC Volpato… - European Journal of …, 2016 - Elsevier
The objective of this study was to determine whether in buccal tissues, after insertion and
removal of coated microneedles, the presence of saliva over the insertion site can lead to …

Hybrid pectin-liposome formulation against multi-resistant bacterial strains

LNM Ribeiro, E de Paula, DA Rossi, GP Monteiro… - Pharmaceutics, 2020 - mdpi.com
This work describes the development of a gastroresistant antimicrobial formulation
composed of two carriers, pectin and liposomes, intended to improve the efficiency of …

Mucoadhesive, thermoreversible hydrogel, containing tetracaine-loaded nanostructured lipid carriers for topical, intranasal needle-free anesthesia

GMF Calixto, BV Muniz, SR Castro, JSM de Araujo… - Pharmaceutics, 2021 - mdpi.com
Recent advances have been reported for needle-free local anesthesia in maxillary teeth by
administering a nasal spray of tetracaine (TTC) and oxymetazoline, without causing pain …