Are sex hormones promising candidates to explain sex disparities in the COVID-19 pandemic?

ML Brandi - Reviews in Endocrine and Metabolic Disorders, 2022 - Springer
Emerging evidence suggests that the novel Coronavirus disease-2019 (COVID-19) is
deadlier for men than women both in China and in Europe. Male sex is a risk factor for …

Sex dimorphism and cancer immunotherapy: May pregnancy solve the puzzle?

FM Venanzi, M Bini, A Nuccio, A De Toma… - Cancer Treatment …, 2023 - Elsevier
In the immunoncology era, growing evidence has shown a clear sex dimorphism in
antitumor immune response with a potential impact on outcomes upon immunecheckpoint …

[HTML][HTML] COVID-19 mortality in Lombardy: the vulnerability of the oldest old and the resilience of male centenarians

G Marcon, M Tettamanti, G Capacci, G Fontanel… - Aging (Albany …, 2020 - ncbi.nlm.nih.gov
Italy was the first European nation to be affected by COVID-19. The biggest cluster of cases
occurred in Lombardy, the most populous Italian region, and elderly men were the …

[HTML][HTML] SARS-CoV-2, immunosenescence and inflammaging: partners in the COVID-19 crime

R Domingues, A Lippi, C Setz, TF Outeiro… - Aging (Albany …, 2020 - ncbi.nlm.nih.gov
Pneumonia outbreak in the city of Wuhan, China, prompted the finding of a novel strain of
severe acute respiratory syndrome virus (SARS-CoV-2). Here, we discuss potential long …

Analysis of T and NK cell subsets in the Sicilian population from young to supercentenarian: The role of age and gender

ME Ligotti, A Aiello, G Accardi, S Aprile… - Clinical & …, 2021 - academic.oup.com
Ageing dramatically affects number and function of both innate and adaptive arms of
immune system, particularly T cell subsets, contributing to reduced vaccination efficacy …

The monocyte-to-lymphocyte ratio: Sex-specific differences in the tuberculosis disease spectrum, diagnostic indices and defining normal ranges

TS Buttle, CY Hummerstone, T Billahalli, RJB Ward… - PloS one, 2021 - journals.plos.org
Background The monocyte-to-lymphocyte ratio (MLR) has been advocated as a biomarker
in tuberculosis. Our objective was to evaluate its clinical value and associations. Methods …

[HTML][HTML] Circulating immune cell phenotypes are associated with age, sex, CMV, and smoking status in the Framingham Heart Study offspring participants

Y Fang, MF Doyle, J Chen, J Mez, CL Satizabal… - Aging (Albany …, 2023 - ncbi.nlm.nih.gov
Understanding the composition of circulating immune cells with aging and the underlying
biologic mechanisms driving aging may provide molecular targets to slow the aging process …

Sex differences in the aging murine urinary bladder and influence on the tumor immune microenvironment of a carcinogen-induced model of bladder cancer

A Hamade, D Li, K Tyryshkin, M Xu, G Conseil… - Biology of sex …, 2022 - Springer
Sex and age associated differences in the tumor immune microenvironment of non-muscle
invasive bladder (NMIBC) cancer and associated clinical outcomes are emerging indicators …

The immune response and aging in chronic inflammatory demyelinating polyradiculoneuropathy

KM Hagen, SS Ousman - Journal of Neuroinflammation, 2021 - Springer
Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) consists of various
autoimmune subtypes in which the peripheral nervous system (PNS) is attacked. CIDP can …

[HTML][HTML] Humoral immunoresponse elicited against an adenoviral-based SARS-CoV-2 coronavirus vaccine in elderly patients

RH Tomas-Grau, C Maldonado-Galdeano… - Aging (Albany …, 2022 - ncbi.nlm.nih.gov
The early sequencing of the SARS-CoV-2 viral genome allowed for a speedy development
of effective vaccines against the virus. Nevertheless, age-related immunosenescence, the …