A novel series of dipeptide derivatives containing indole-3-carboxylic acid conjugates as potential antimicrobial agents: the design, solid phase peptide synthesis, in …

SR Tivari, SV Kokate, E Delgado-Alvarado, MS Gayke… - RSC …, 2023 - pubs.rsc.org
A new library of peptide-heterocycle hybrids consisting of an indole-3-carboxylic acid
constituent conjugated with short dipeptide motifs was designed and synthesized by using …

Chimeric nanobody-decorated liposomes by self-assembly

MM Rahman, J Wang, G Wang, Z Su, Y Li… - Nature …, 2024 - nature.com
Liposomes as drug vehicles have advantages, such as payload protection, tunable carrying
capacity and improved biodistribution. However, due to the dysfunction of targeting moieties …

Hybrid Planar Copolymer Membranes with Dual Functionality against Bacteria Growth

M Bina, JP Coats, M Skowicki, M Malekovic, V Mihali… - Langmuir, 2024 - ACS Publications
Antibacterial surfaces can be classified into two categories: passive surfaces, which repel
bacteria by affecting surface wettability, and active surfaces, which have bactericidal …

Synthesis and Evaluation of Biological Activities for a Novel 1, 2, 3, 4-Tetrahydroisoquinoline Conjugate with Dipeptide Derivatives: Insights from Molecular Docking …

SR Tivari, SV Kokate, JL Belmonte-Vázquez… - ACS …, 2023 - ACS Publications
Peptide synthesis has opened new frontiers in the quest for bioactive molecules with
limitless biological applications. This study presents the synthesis of a series of novel …

[HTML][HTML] Vaccine delivery systems and administration routes: Advanced biotechnological techniques to improve the immunization efficacy

A Bouazzaoui, AAH Abdellatif - Vaccine: X, 2024 - Elsevier
Since the first use of vaccine tell the last COVID-19 pandemic caused by spread of SARS-
CoV-2 worldwide, the use of advanced biotechnological techniques has accelerated the …

Tryptophan End-Tagging Confers Antifungal Activity on a Tick-Derived Peptide by Triggering Reactive Oxygen Species Production

CK Chiramba, DS Möller, CD Lorenz… - ACS …, 2024 - ACS Publications
WHO has identified several Candida species including Candida albicans as critical priority
fungal pathogens due to greater infection prevalence and formation of recalcitrant biofilms …

Effect of tryptophan position and lysine/arginine substitution in antimicrobial peptides on antifungal action

YM Kim, SC Park, Y Yoon, MK Jang, JR Lee - Biochemical and Biophysical …, 2024 - Elsevier
Every year, the overprescription, misuse, and improper disposal of antibiotics have led to the
rampant development of drug-resistant pathogens and, in turn, a significant increase in the …

Tryptophan end-tagging enhances the antifungal activity of a salt-sensitive tick-derived peptide by inducing reactive oxygen species production

D Möller, C Lorenz, R Chirombo, J Mason, M Bester… - ACS Omega, 2024 - kclpure.kcl.ac.uk
The WHO has identified several Candida species including C. albicans as critical priority
fungal pathogens due to greater infection prevalence and formation of recalcitrant biofilms …

Design and Characterization of Anticancer Peptides Derived from Snake Venom Metalloproteinase Library

S Saranya, M Bharathi, NS Kumar… - International Journal of …, 2024 - Springer
Snake venom metalloproteinases (SVMPs) are enzymatic proteins found in snake venom
and are known for their diverse biological activities, including induction of hemorrhage and …

Cell-translocation mechanisms of CPPs

Ü Langel - CPP, Cell-Penetrating Peptides, 2023 - Springer
Here, the complicated cellular entry mechanism (s) ofCPPs andCPP/cargo conjugates will
be summarized. Both, direct and endocytotic cellular uptake of CPPs efficiently co-exist …