The zinc finger and BTB (broad-complex, tramtrack and bric a brac) domain containing
protein 7A (ZBTB7A) is a pleiotropic transcription factor that plays an important role in …

Glucocorticoid receptor (GR) is a transcription factor that plays a crucial role in cancer
biology. In this study, we utilized an in silico‐designed GR activity signature to demonstrate …

The cellular fate after infection with human coronaviruses (HCoVs) is typically death.
Previous data suggest, however, that the transcriptional state of an individual cell may …

Prostate cancer (PCa) is commonly occurred with high incidence in men worldwide, and
many patients will be eventually suffered from the dilemma of castration-resistance with the …

The androgen receptor (AR) plays a pivotal role in driving prostate cancer (PCa)
development. However, when stimulated by high levels of androgens, AR can also function …

Glioblastoma multiforme (GBM), the most aggressive and malignant glioma, has a poor
prognosis. Although patients with GBM are treated with surgery, chemotherapy, and …

The androgen receptor (AR) is a central driver of aggressive prostate cancer. After initial
treatment with androgen receptor signaling inhibitors (ARSi), reactivation of AR signaling …

The androgen receptor (AR) pathway regulates key cell survival programs in prostate
epithelium. The AR represents a near-universal driver and therapeutic vulnerability in …

Lack of diversity and proportionate representation in genomics datasets and databases
contributes to inequity in healthcare outcomes globally. The relationships of human diversity …

Background Zinc finger and BTB domain-containing 7A (ZBTB7A) is a member of the POK
family of transcription factors that plays an oncogenic or tumor-suppressive role in different …