A preparation method for mRNA-LNPs with improved properties

C Geng, K Zhou, Y Yan, C Li, B Ni, J Liu, Y Wang… - Journal of Controlled …, 2023 - Elsevier
The properties of mRNA lipid nanoparticles (mRNA-LNPs), including size, empty particles,
morphology, storage stability, and transfection potency, are critically dependent on the …

[HTML][HTML] Viral entry inhibitors protect against SARS-CoV-2-induced neurite shortening in differentiated SH-SY5Y cells

M Mignolet, J Gilloteaux, N Halloin, M Gueibe… - Viruses, 2023 - mdpi.com
The utility of human neuroblastoma cell lines as in vitro model to study neuro-invasiveness
and neuro-virulence of SARS-CoV-2 has been demonstrated by our laboratory and others …

[HTML][HTML] Interaction of copper potential metallodrugs with TMPRSS2: A comparative study of docking tools and its implications on COVID-19

S Vazquez-Rodriguez, D Ramírez-Contreras… - Frontiers in …, 2023 - frontiersin.org
SARS-CoV-2 is the virus responsible for the COVID-19 pandemic. For the virus to enter the
host cell, its spike (S) protein binds to the ACE2 receptor, and the transmembrane protease …

[HTML][HTML] Symmetrical peripheral gangrene: potential mechanisms and therapeutic approaches in severe COVID-19

M Wang, T Sun, L Dong, S Huang… - Frontiers in …, 2023 - ncbi.nlm.nih.gov
Symmetrical peripheral gangrene is a rare condition that is characterized by ischemic
damage and tissue death (gangrene) in the extremities. Recent reports have shed light on …

[HTML][HTML] Dicoumarol is an effective post-exposure prophylactic for SARS-CoV-2 Omicron infection in human airway epithelium

Y Peng, S Chen, Z Wang, Z Zhou, J Sun… - … and Targeted Therapy, 2023 - nature.com
Repurposing existing drugs to inhibit SARS-CoV-2 infection in airway epithelial cells (AECs)
is a quick way to find novel treatments for COVID-19. Computational screening has found …

The Potential Role of Medicinal Plants, Traditional Herbal Medicines, and Formulations to Overcome SARS-CoV-2 Induced Health Crisis

M Halder, R Bose, S Jha - Medicinal Plants: Biodiversity, Biotechnology …, 2023 - Springer
Since December 2019, the infection of Severe Acute Respiratory Syndrome-related
Coronavirus 2 (SARS-CoV-2), also known as novel coronavirus, has been responsible for …

Anti-coronavirus and anti-pulmonary inflammation effects of iridoids, the common component from Chinese herbal medicines for the treatment of COVID-19

DY Huang, YX Luo, WD Zheng, SY Wu… - Journal of Natural …, 2024 - Springer
The practice of Chinese herbal medicines for the treatment of COVID-19 in China played an
essential role for the control of mortality rate and reduction of recovery time. The iridoids is …