Red blood cells (RBCs) have historically been considered passive bystanders in
thrombosis. However, clinical and epidemiological studies have associated quantitative and …

Acute chest syndrome (ACS) is a frequent cause of acute lung disease in children with sickle
cell disease (SCD). Patients may present with ACS or may develop this complication during …

In spite of significant strides in the treatment of sickle cell disease (SCD), SCD crises are still
responsible for high morbidity and early mortality. While most patients initially seek care in …

Deep vein thrombosis and pulmonary embolism, collectively termed venous
thromboembolism (VTE), affect over 1 million Americans each year. VTE is triggered by …

BACKGROUND: Sickle cell disease is recognized as a hypercoagulable state; however, the
frequency and characteristics of venous thromboembolism in sickle cell patients have not …

Background Venous thromboembolism (VTE) has been recently recognized as a
complication of sickle cell disease (SCD); however, the incidence of VTE in SCD is …

Sickle cell disease is the most common inherited haematological disorder that leads to the
irreversible damage of multiple organs. Although sickling of red blood cells and vaso …

Sickle cell disease (SCD) is a hypercoagulable state. Patients exhibit increased platelet
activation, high plasma levels of markers of thrombin generation, depletion of natural …

Previous reports show increased incidence of venous thromboembolism [VTE, deep‐vein
thrombosis (DVT) and pulmonary embolus (PE)] in sickle cell disease (SCD) patients but did …

Venous thromboembolism (VTE) is common in patients with sickle cell disease (SCD). The
etiology of increased risk of VTE in SCD patients is multifactorial and is related to both …