Gastric cancer is a prevalent yet heterogeneous disease. From diet and lifestyle to genetics
and ethnicity, our appreciation of the complexity of gastric cancer has evolved. This review …

Tumorigenesis has long been thought to be a multistep process (Foulds, 1958); however,
only recently has it become possible to identify the molecular events that underlie the …

Many patients suffering from developmental disorders harbor submicroscopic deletions or
duplications that, by affecting the copy number of dosage-sensitive genes or disrupting …

This book is the third volume of the 4th Edition of the WHO series on histological and genetic
typing of human tumours. It is an authoritative, concise reference book providing an …

Simple Summary Colorectal cancer (CRC) is the second-leading cause of cancer-related
deaths worldwide. In this review article, we examine the role of gut microbiota in the …

A large body of evidence supports the idea that accumution of mutant APC alleles in affected
kindreds (Groden lated genetic changes underlie the development of neoet al., 1991; …

DNA from 61 unrelated patients with adenomatous polyposis coli (APC) was examined for
mutations in three genes@ Pi, SRP79, and DP2. 5) located within a 166 kb region deleted in …

Colorectal cancer (CRC) is the third most common diagnosed malignancy among both
sexes in the United States as well as in the European Union. While the incidence and …

Recent studies suggest that one or more genes on chromosome 5q21 are important for the
development of colorectal cancers, particularly those associated with familial adenomatous …

Previous studies have demonstrated that allelic deletions of the short arm of chromosome 17
occur in over 75% of colorectal carcinomas. Twenty chromosome 17p markers were used to …