Extracellular vesicles and exosomes: insights from exercise science

JP Nederveen, G Warnier, A Di Carlo… - Frontiers in …, 2021 - frontiersin.org
The benefits of exercise on health and longevity are well-established, and evidence
suggests that these effects are partially driven by a spectrum of bioactive molecules …

[HTML][HTML] Influences of age, race, and sex on extracellular vesicle characteristics

NN Hooten, AM Byappanahalli, M Vannoy… - Theranostics, 2022 - ncbi.nlm.nih.gov
Recent attention has focused on the use of extracellular vesicles (EVs) as biological
indicators of health and disease. These small, nano-sized membrane bound vesicles are …

Metabolic architecture of acute exercise response in middle-aged adults in the community

M Nayor, RV Shah, PE Miller, JB Blodgett, M Tanguay… - Circulation, 2020 - Am Heart Assoc
Background: Whereas regular exercise is associated with lower risk of cardiovascular
disease and mortality, mechanisms of exercise-mediated health benefits remain less clear …

Effects of exercise on exosome release and cargo in in vivo and ex vivo models: A systematic review

B Estébanez, D Jiménez‐Pavón… - Journal of cellular …, 2021 - Wiley Online Library
Exercise‐released exosomes have been identified as novel players to mediate cell‐to‐cell
communication in promoting systemic beneficial effects. This review aimed to systematically …

Circulating exosome‐like vesicle and skeletal muscle microRNAs are altered with age and resistance training

D Xhuti, MI Nilsson, K Manta… - The Journal of …, 2023 - Wiley Online Library
The age‐related loss of skeletal muscle mass and functionality, known as sarcopenia, is a
critical risk factor for morbidity and all‐cause mortality. Resistance exercise training (RET) is …

The role of biomechanical stress in extracellular vesicle formation, composition and activity

W Thompson, ET Papoutsakis - Biotechnology Advances, 2023 - Elsevier
Extracellular vesicles (EVs) are cornerstones of intercellular communication with exciting
fundamental, clinical, and more broadly biotechnological applications. However, variability …

From sweat to hope: The role of exercise‐induced extracellular vesicles in cancer prevention and treatment

A Llorente, A Brokāne, A Mlynska… - Journal of …, 2024 - Wiley Online Library
The benefits of regular physical exercise on cancer prevention, as well as reducing fatigue,
treatment side effects and recurrence, and improving quality of life and overall survival of …

Skeletal muscle releases extracellular vesicles with distinct protein and microRNA signatures that function in the muscle microenvironment

S Watanabe, Y Sudo, T Makino, S Kimura… - PNAS …, 2022 - academic.oup.com
Extracellular vesicles (EVs) contain various regulatory molecules and mediate intercellular
communications. Although EVs are secreted from various cell types, including skeletal …

The multiple faces of extracellular vesicles released by microglia: Where are we 10 years after?

M Gabrielli, S Raffaele, M Fumagalli… - Frontiers in Cellular …, 2022 - frontiersin.org
As resident component of the innate immunity in the central nervous system (CNS),
microglia are key players in pathology. However, they also exert fundamental roles in brain …

Extracellular vesicles as drivers of immunoinflammation in atherothrombosis

R Suades, MF Greco, T Padró, L Badimon - Cells, 2022 - mdpi.com
Atherosclerotic cardiovascular disease is the leading cause of morbidity and mortality all
over the world. Extracellular vesicles (EVs), small lipid-bilayer membrane vesicles released …