The precise construction of chiral molecules is a core research area in chemical science and
technology. Among the plethora of reported synthetic methods, asymmetric catalysis has …

A survey of protein databases indicates that the majority of enzymes exist in oligomeric
forms, with about half of those found in the UniProt database being homodimeric …

The development of a reliable strategy for stereodivergent radical reactions that allows
convenient access to all stereoisomers of homocoupling adducts with multiple stereogenic …

The stereodivergent synthesis of allene compounds bearing α, β‐adjacent central chiralities
has been realized via the Pd/Cu‐catalyzed dynamic kinetic asymmetric alkylation of racemic …

Herein, we report a synthesis of cyclohexanones bearing multi‐continuous stereocenters by
combining copper‐catalyzed asymmetric conjugate addition of dialkylzinc reagents to cyclic …

Fluorinated amino acids and related peptides/proteins have been found widespread
applications in pharmaceutical and agricultural compounds. However, strategies for …

The construction of acyclic, non‐adjacent 1, 3‐stereogenic centers, prevalent motifs in drugs
and bioactive molecules, has been a long‐standing synthetic challenge due to acyclic …

Herein, we report a one‐pot method for enantioselective C− H allylation of pyridines at C3
via tandem borane and palladium catalysis. This method involves borane‐catalyzed …

Synergistic catalysis has emerged as one of the most powerful tools for stereodivergent
formation of Csp3− Csp3 bonds bearing vicinal stereocenters. Despite the many successes …

The precise control of Z and E configurations of the carbon-carbon double bond in alkene
synthesis has long been a fundamental challenge in synthetic chemistry, even more …