Approximately 6% of adults worldwide have atherosclerosis and thrombosis of the lower
limb arteries (peripheral artery disease (PAD)) and the prevalence is rising. PAD causes leg …

Many patients with chest pain undergoing coronary angiography do not show significant
obstructive coronary lesions. A substantial proportion of these patients have abnormalities in …

Systemic vascular inflammation plays multiple maladaptive roles which contribute to the
progression and destabilization of atherosclerotic cardiovascular disease (ASCVD). These …

Despite the enormous progress in the understanding of the course of the ischemic stroke
over the last few decades, a therapy that effectively protects neurovascular units (NVUs) and …

Background Chronic inflammation is a process sustained by the augmentation of circulating
cytokines level and C-reactive protein (CRP). Adipocytes and adipose tissue infiltration with …

Peripheral arterial disease (PAD) of the lower extremities is a chronic illness predominantly
of atherosclerotic aetiology, associated to traditional cardiovascular (CV) risk factors. It is …

Cardiovascular disease (CVD) still being the most common cause of death in worldwide. In
spite of development of new lipid-lowering therapies which optimize low-density lipoprotein …

Objective: Patients with lower extremity peripheral artery disease (PAD) are at increased risk
of major adverse cardiovascular events. Numerous plasma biomarkers have been …

The most serious long-term effects of diabetes is peripheral artery disease (PAD) which
increases the chance of developing diabetic foot ulcers, gangrene and even lower limb …

Purpose Breast cancer patients receiving hormonal therapies face risks of relapse,
increased rates of cardiovascular events, and toxicities of therapy such as aromatase …