Pregnancy-specific glycoproteins: evolution, expression, functions and disease associations

T Moore, JM Williams, MA Becerra-Rodriguez… - …, 2022 - rep.bioscientifica.com
Pregnancy-specific glycoproteins (PSGs) are members of the immunoglobulin superfamily
and are closely related to the predominantly membrane-bound CEACAM proteins. PSGs are …

Medawar's PostEra: galectins emerged as key players during fetal-maternal glycoimmune adaptation

E Menkhorst, NG Than, U Jeschke… - Frontiers in …, 2021 - frontiersin.org
Lectin-glycan interactions, in particular those mediated by the galectin family, regulate many
processes required for a successful pregnancy. Over the past decades, increasing evidence …

Roles of N-linked glycosylation and glycan-binding proteins in placentation: trophoblast infiltration, immunomodulation, angiogenesis, and pathophysiology

Z Huang, PF Lai, ATH Cocker… - Biochemical Society …, 2023 - portlandpress.com
Protein N-linked glycosylation is a structurally diverse post-translational modification that
stores biological information in a larger order of magnitude than other post-translational …

[HTML][HTML] Unveiling the hidden players: the crucial role of transposable elements in the placenta and their potential contribution to pre-eclampsia

LM Keighley, CF Lynch-Sutherland, SN Almomani… - Placenta, 2023 - Elsevier
The human placenta is a vital connection between maternal and fetal tissues, allowing for
the exchange of molecules and modulation of immune interactions during pregnancy …

Pregnancy-specific beta-1-glycoprotein 6 is a potential novel diagnostic biomarker of placenta accreta spectrum

H Kashiwagi, T Mariya, M Umemoto, S Ogawa… - Medical molecular …, 2024 - Springer
Early diagnosis is essential for the safer perinatal management of placenta accreta spectrum
(PAS). We used transcriptome analysis to investigate diagnostic maternal serum biomarkers …

A unique maternal and placental galectin signature upon SARS-CoV-2 infection suggests galectin-1 as a key alarmin at the maternal–fetal interface

F Zhao, AC Tallarek, Y Wang, Y Xie, A Diemert… - Frontiers in …, 2023 - frontiersin.org
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic imposed a
risk of infection and disease in pregnant women and neonates. Successful pregnancy …

First Trimester Placental Biomarkers for Pregnancy Outcomes

M Cristodoro, M Messa, G Tossetta, D Marzioni… - International Journal of …, 2024 - mdpi.com
The placenta plays a key role in several adverse obstetrical outcomes, such as
preeclampsia, intrauterine growth restriction and gestational diabetes mellitus. The early …

[HTML][HTML] Modulation of galectin-9 mediated responses in monocytes and T-cells by pregnancy-specific glycoprotein 1

M Mendoza, A Ballesteros, E Rendon-Correa… - Journal of Biological …, 2024 - Elsevier
Successful pregnancy relies on a coordinated interplay between endocrine, immune, and
metabolic processes to sustain fetal growth and development. The orchestration of these …

[HTML][HTML] Different Proteomic Profiles Regarding Antihypertensive Therapy in Preeclampsia Pregnant

CC Pinto-Souza, JNS Kaihara, PR Nunes… - International Journal of …, 2024 - mdpi.com
Preeclampsia (PE) is a hypertensive pregnancy syndrome associated with target organ
damage and increased cardiovascular risks, necessitating antihypertensive therapy …

Morfofunctional and Molecular Changes in Placenta and Peripheral Blood in Preeclampsia and Gestational Diabetes Mellitus

KA Artemieva, YV Stepanova, II Stepanova… - Doklady Biological …, 2023 - Springer
Gestational diabetes mellitus (GDM) and preeclampsia (PE) are common pregnancy
complications with similar risk factors. Although GDM is associated with PE, the exact …