The ionome is defined as the mineral nutrient and trace element composition of an organism
and represents the inorganic component of cellular and organismal systems. Ionomics, the …

Background The production of peroxide and superoxide is an inevitable consequence of
aerobic metabolism, and while these particular'reactive oxygen species'(ROSs) can exhibit a …

With biomedical literature increasing at a rate of several thousand papers per week, it is
impossible to keep abreast of all developments; therefore, automated means to manage the …

Unlike signalling pathways, metabolic networks are subject to strict stoichiometric
constraints. Metabolomics amplifies changes in the proteome, and represents more closely …

Many scientists now manage the bulk of their bibliographic information electronically,
thereby organizing their publications and citation material from digital libraries. However, a …

Despite the dramatic growth of the Internet, the number of practical applications in drug
design, particular for prediction ADME/T properties, which are available on-line remains …

Drug discovery is a time consuming and costly process. Recently, a trend towards the use of
in silico computational chemistry and molecular modeling for computer-aided drug design …

Background There is a need for software applications that provide users with a complete
and extensible toolkit for chemo-and bioinformatics accessible from a single workbench …

The newly emerging field of systems biology involves a judicious interplay between high‐
throughput 'wet'experimentation, computational modelling and technology development …

Technological advances in high-throughput screening methods, combinatorial chemistry
and the design of virtual libraries have evolved in the pursuit of challenging drug targets …