Classical and noncanonical functions of miRNAs in cancers

MP Dragomir, E Knutsen, GA Calin - Trends in Genetics, 2022 - cell.com
Alterations in microRNAs (miRNAs) expression are causative in the initiation and
progression of human cancers. The molecular events responsible for the widespread …

MicroRNA let-7 and viral infections: focus on mechanisms of action

A Letafati, S Najafi, M Mottahedi, M Karimzadeh… - Cellular & Molecular …, 2022 - Springer
MicroRNAs (miRNAs) are fundamental post-transcriptional modulators of several critical
cellular processes, a number of which are involved in host defense mechanisms. In …

The miRNA: a small but powerful RNA for COVID-19

S Zhang, K Amahong, X Sun, X Lian, J Liu… - Briefings in …, 2021 - academic.oup.com
Abstract Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) is a severe and rapidly evolving epidemic. Now …

Epigenetic regulator miRNA pattern differences among SARS-CoV, SARS-CoV-2, and SARS-CoV-2 world-wide isolates delineated the mystery behind the epic …

MAAK Khan, MRU Sany, MS Islam… - Frontiers in genetics, 2020 - frontiersin.org
A detailed understanding of the molecular mechanism of SARS-CoV-2 pathogenesis is still
elusive, and there is a need to address its deadly nature and to design effective …

RNAInter in 2020: RNA interactome repository with increased coverage and annotation

Y Lin, T Liu, T Cui, Z Wang, Y Zhang, P Tan… - Nucleic acids …, 2020 - academic.oup.com
Research on RNA-associated interactions has exploded in recent years, and increasing
numbers of studies are not limited to RNA–RNA and RNA–protein interactions but also …

ABCB1 and ABCG2 regulation at the blood-brain barrier: potential new targets to improve brain drug delivery

JA Schulz, AMS Hartz, B Bauer, M Gottesman - Pharmacological Reviews, 2023 - Elsevier
The drug efflux transporters ABCB1 and ABCG2 at the blood-brain barrier limit the delivery
of drugs into the brain. Strategies to overcome ABCB1/ABCG2 have been largely …

Comparative analyses of SAR-CoV2 genomes from different geographical locations and other coronavirus family genomes reveals unique features potentially …

R Sardar, D Satish, S Birla, D Gupta - BioRxiv, 2020 - biorxiv.org
The ongoing pandemic of the coronavirus disease 2019 (COVID-19) is an infectious disease
caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV2). We have …

MicroRNAs; their therapeutic and biomarker properties

S Azizi Dargahlou, M Iriti, M Pouresmaeil… - Cellular, Molecular …, 2023 - cmbr-journal.com
MicroRNAs (miRNAs) are, small (roughly 19–25 nucleotides in length), conserved, non-
coding, single-stranded, and functional RNA molecules with the properties of gene …

Integrating multi-omics to unravel host-microbiome interactions in inflammatory bowel disease

Y Zhang, JP Thomas, T Korcsmaros, L Gul - Cell Reports Medicine, 2024 - cell.com
The gut microbiome is crucial for nutrient metabolism, immune regulation, and intestinal
homeostasis with changes in its composition linked to complex diseases like inflammatory …

Mitigating off‐target effects of small RNAs: conventional approaches, network theory and artificial intelligence

Z Bereczki, B Benczik, OM Balogh… - British Journal of …, 2025 - Wiley Online Library
Three types of highly promising small RNA therapeutics, namely, small interfering RNAs
(siRNAs), microRNAs (miRNAs) and the RNA subtype of antisense oligonucleotides (ASOs) …