Discovered serendipitously over thirty years ago [1], cisplatin (cA-diamminedichloroplatinum
(II)) is used to treat breast, ovarian, bladder, lung, and head and neck carcinomas and …

Biological targets, such as proteins and nucleic acids, are chiral, therefore stereoisomers of
chiral molecules interact with these targets differently and, indeed, the antitumor drug …

Spectroscopic Properties of Inorganic and Organometallic Compounds provides a unique
source of information on an important area of chemistry. Divided into sections mainly …

Insight into the N7/O6 equatorial binding interactions of the antitumor active complex Rh2
(OAc) 4 (H2O) 2 (OAc-= CH3CO2-) with the nucleotide 5 '-GMP and the DNA fragment d …

Selective binding of coordinating agents (cisplatin) to target molecules (DNA) and the
contribution of H-bonding, electrostatic interactions, and steric effects in such binding are …

We have prepared four complexes of the type [Re (guanine) 2 (X)(CO) 3](guanine= 9-
methylguanine or 7-methylguanine, X= H2O or Br) in order to understand the factors …

Complexes of the types L PtCl2 and [L 2Pt] X2 [L= substituted 3-(pyridin-2 '-yl)-1, 2, 4-
triazine] were synthesized and characterized by NMR spectroscopy and, for the first time, by …

Me 4 DAB Pt G 2 adducts with the bulky C 2-symmetric chiral diamine, Me 4 DAB (N, N, N′,
N′-tetramethyl-2, 3-diaminobutane with R, R and S, S configurations at the chelate ring C …

The highly distorted Pt (d (G* pG*))(G*= N7-platinated G) 17-membered macrocyclic ring
formed by cisplatin anticancer drug binding to DNA alters the structure of the G* G* base pair …

Anticancer-active monofunctional Pt (II) complexes have bulky carrier ligands and bind to G
residues in DNA, causing structural distortions. To gain fundamental chemical information …