Protein pharmaceuticals have become a significant class of marketed drug products and are
expected to grow steadily over the next decade. Development of a commercial protein …

Formation and accumulation of protein aggregates adversely affect intracellular processes
in living cells and are negative factors in the production and storage of protein preparations …

Dynamic light scattering (DLS) is a ubiquitous tool for the characterisation of hydrodynamic
particle size in dispersion, relying on diffusive-only sample motion and exquisite thermal …

An enormous population worldwide is presently confronted with debilitating
neurodegenerative diseases. The etiology of the disease is connected to protein …

Several factors may affect erythropoietin (EPO) sugar structures including designing cell
culture procedure, pH, concentration of additives, dissolved oxygen, and other …

In recombinant protein production, over-expressed genes induce unfolded protein response
(UPR), overloaded protein aggregation in endoplasmic reticulum and its expansion. In this …

蛋白质聚集在生物医药生产中是一个关键问题. 在蛋白质的生产, 运输和储存的过程中,
多种因素都能导致蛋白质发生聚集. 随着对蛋白质聚集这一现象的深入研究 …

Solution scattering techniques offer several complementary approaches for characterizing
the biophysical properties and higher-order structure of protein biopharmaceuticals. These …

The formation and accumulation of protein aggregates adversely affect intracellular
processes in a living cell and are a negative factor in the production and storage of protein …