Astrocytes, oligodendrocytes, and microglia are abundant cell types found in the central
nervous system and have been shown to play crucial roles in regulating both normal and …

The astronomical increase of the world's aged population is associated with the increased
prevalence of neurodegenerative diseases, heightened disability, and extremely high costs …

Astrocytes regulate central nervous system development, maintain its homeostasis and
orchestrate repair upon injury. Emerging evidence support functional specialization of …

Frailty is a geriatric syndrome associated with both locomotor and cognitive decline, typically
linked to chronic systemic inflammation, ie, inflammaging. In the current study, we …

Astrocytes are emerging in the neuroscience field as crucial modulators of brain functions,
from the molecular control of synaptic plasticity to orchestrating brain-wide circuit activity for …

A number of age-associated neurodegenerative diseases, including Alzheimer's disease
(AD), Parkinson's disease (PD) and amyotrophic lateral sclerosis (ALS), possess a shared …

Background Salidroside is the major bioactive and pharmacological active substance in
Rhodiola rosea L. It has been reported to have neuroprotective effects on cerebral …

The main pathological feature of the neurodegenerative diseases is represented by
neuronal death that represents the final step of a cascade of adverse/hostile events. Early in …

Approximately one-third of individuals with major depressive disorder are resistant to
conventional antidepressants (ie, monoamine-based therapies), and, even among …

Traumatic brain injury (TBI) remains the leading cause of long-term disability, which
annually involves millions of individuals. Several studies on mammals reported that …