Severe traumatic brain injury: targeted management in the intensive care unit

N Stocchetti, M Carbonara, G Citerio, A Ercole… - The Lancet …, 2017 - thelancet.com
Severe traumatic brain injury (TBI) is currently managed in the intensive care unit with a
combined medical–surgical approach. Treatment aims to prevent additional brain damage …

Consensus summary statement of the international multidisciplinary consensus conference on multimodality monitoring in neurocritical care: a statement for …

P Le Roux, DK Menon, G Citerio, P Vespa, MK Bader… - Neurocritical care, 2014 - Springer
Neurocritical care depends, in part, on careful patient monitoring but as yet there are little
data on what processes are the most important to monitor, how these should be monitored …

Cerebral blood flow and autoregulation: current measurement techniques and prospects for noninvasive optical methods

S Fantini, A Sassaroli, KT Tgavalekos… - …, 2016 - spiedigitallibrary.org
Cerebral blood flow (CBF) and cerebral autoregulation (CA) are critically important to
maintain proper brain perfusion and supply the brain with the necessary oxygen and energy …

Real-time continuous monitoring of cerebral blood flow autoregulation using near-infrared spectroscopy in patients undergoing cardiopulmonary bypass

K Brady, B Joshi, C Zweifel, P Smielewski, M Czosnyka… - Stroke, 2010 - Am Heart Assoc
Background and Purpose—Individualizing mean arterial blood pressure targets to a
patient's cerebral blood flow autoregulatory range might prevent brain ischemia for patients …

Monitoring the injured brain: ICP and CBF

LA Steiner, PJD Andrews - BJA: British Journal of Anaesthesia, 2006 - academic.oup.com
Raised intracranial pressure (ICP) and low cerebral blood flow (CBF) are associated with
ischaemia and poor outcome after brain injury. Therefore, many management protocols …

Monitoring of cerebrovascular autoregulation: facts, myths, and missing links

M Czosnyka, K Brady, M Reinhard, P Smielewski… - Neurocritical care, 2009 - Springer
The methods for continuous assessment of cerebral autoregulation using correlation, phase
shift, or transmission (either in time-or frequency-domain) were introduced a decade ago …

Clinical relevance of cerebral autoregulation following subarachnoid haemorrhage

KP Budohoski, M Czosnyka, PJ Kirkpatrick… - Nature Reviews …, 2013 - nature.com
Subarachnoid haemorrhage (SAH) is a form of stroke that is associated with substantial
morbidity, often as a result of cerebral ischaemia that occurs in the following days. These …

The lower limit of reactivity as a potential individualised cerebral perfusion pressure target in traumatic brain injury: a CENTER-TBI high-resolution sub-study analysis

E Beqiri, FA Zeiler, A Ercole, MM Placek, J Tas… - Critical Care, 2023 - Springer
Background A previous retrospective single-centre study suggested that the percentage of
time spent with cerebral perfusion pressure (CPP) below the individual lower limit of …

Monitoring of intracranial pressure in patients with traumatic brain injury

C Hawthorne, I Piper - Frontiers in neurology, 2014 - frontiersin.org
Since Monro published his observations on the nature of the contents of the intracranial
space in 1783, there has been investigation of the unique relationship between the contents …

Nonconvulsive seizures after subarachnoid hemorrhage: multimodal detection and outcomes

J Claassen, A Perotte, D Albers, S Kleinberg… - Annals of …, 2013 - Wiley Online Library
Objective Seizures have been implicated as a cause of secondary brain injury, but the
systemic and cerebral physiologic effects of seizures after acute brain injury are poorly …