Organ-on-a-Chip (OOC) technology, which emulates the physiological environment and
functionality of human organs on a microfluidic chip, is undergoing significant technological …

The COVID-19 pandemic has driven the scientific community to adopt an efficient and
reliable model that could keep up with the infectious disease arms race. Coinciding with the …

There is a need for better predictive models of the human immune system to evaluate safety
and efficacy of immunomodulatory drugs and biologics for successful product development …

The Helicobacter pylori infection in the stomach is the key reason for gastric mucosal
bleeding. Eliminating gastric Helicobacter pylori by oral treatment remains difficult due to the …

Gastrointestinal organ failure, from congenital or postnatally acquired pathologies, is a major
cause of death across countries of all income levels. Organoids and engineered tissues …

Biophysical factors play a fundamental role in human embryonic development. Traditional in
vitro models of organogenesis focused on the biochemical environment and did not …

Abstract Organ‐On‐a‐Chip (OOC) is a multichannel 3D‐microfluidic cell‐culture system
incorporated in a chip that simulates the behavior of an organ. This technology relies on a …

The basal side of these mucosoids interacts with soluble factors through the culture medium
and produces mucus, similar to natural conditions. To study the effects of prolonged …

Gastrointestinal organoids have emerged as a model system that authentically recapitulates
the in vivo situation. Despite biomedical and technical challenges, self-assembled 3D …