[HTML][HTML] Curcumin: A golden approach to healthy aging: A systematic review of the evidence

YC Nunes, NM Mendes, E Pereira de Lima… - Nutrients, 2024 - mdpi.com
Aging-related disorders pose significant challenges due to their complex interplay of
physiological and metabolic factors, including inflammation, oxidative stress, and …

Impact of α-Globin Gene Expression and α-Globin Modifiers on the Phenotype of β-Thalassemia and Other Hemoglobinopathies: Implications for Patient Management

J Traeger-Synodinos, C Vrettou, C Sofocleous… - International Journal of …, 2024 - mdpi.com
In this short review, we presented and discussed studies on the expression of globin genes
in β-thalassemia, focusing on the impact of α-globin gene expression and α-globin modifiers …

[HTML][HTML] A natural small molecule aspidosperma-type alkaloid, hecubine, as a new TREM2 activator for alleviating lipopolysaccharide-induced neuroinflammation in …

L Li, YL He, N Xu, XF Wang, B Song, BQ Tang… - Redox Biology, 2024 - Elsevier
Neuroinflammation and oxidative stress play a crucial role in the pathogenesis of
neurodegenerative diseases, including Alzheimer's disease. The triggering receptor …

[HTML][HTML] Deciphering Oxidative Stress in Cardiovascular Disease Progression: A Blueprint for Mechanistic Understanding and Therapeutic Innovation

Z Zhang, J Guo - Antioxidants, 2024 - mdpi.com
Oxidative stress plays a pivotal role in the pathogenesis and progression of cardiovascular
diseases (CVDs). This review focuses on the signaling pathways of oxidative stress during …

Portulaca oleracea L seed extracts counteract diabetic nephropathy through SDF-1/IL10/PPARγ–mediated tuning of keap1/Nrf2 and NF-κB transcription in Sprague …

WM Aziz, SA Ahmed, SE Shaker, DB Fayed… - Diabetology & Metabolic …, 2024 - Springer
Background & objective: While oxidative stress is the key player driving diabetic
nephropathy (DN), firm glycemic control remains the pillar prophylactic measure. Purslane …

Nrf2: a key regulator in chemoradiotherapy resistance of osteosarcoma

X Peng, J Feng, H Yang, P Xia, F Pu - Genes & Diseases, 2024 - Elsevier
Osteosarcoma (OS), frequently observed in children and adolescents, is one of the most
common primary malignant tumors of the bone known to be associated with a high capacity …

β‐CARYOPHYLLENE ATTENUATES OXIDATIVE STRESS AND INFLAMMATORY RESPONSE IN ACUTE LUNG INJURY BY REGULATING Nrf2/HO-1/NF-κB AND …

P Niri, A Saha, S Polopalli, M Kumar, S Das… - Biochemical and …, 2025 - Elsevier
Acute lung injury (ALI) and its severe form, acute respiratory distress syndrome (ARDS), is a
clinical syndrome that can cause pulmonary edema, inflammation, oxidative stress, and …

[HTML][HTML] Effects of Caffeic Acid Phenethyl Ester on Embryonic Development Through Regulation of Mitochondria and Endoplasmic Reticulum

CM Huang, HM Huang, YH Li, XW Liang, NH Kim… - Veterinary …, 2024 - mdpi.com
Caffeic acid phenethyl ester (CAPE) is one of the main active components of the natural
medicine propolis, which has antioxidant, anti-tumor, and immunomodulatory activities. This …

Intracellular iron accumulation induces inflammatory and oxidative status of the host after Japanese encephalitis viral infection

G Singh, A Singh, S Mishra, D Singh, A Kumar - Molecular Neurobiology, 2024 - Springer
The factors mitigating the microglia/macrophage activation and inflammatory damage in
Japanese encephalitis (JE) virus infected CNS are still being ascertained. We aim to …

Globin associated oxidative stress

BJ Reeder - Antioxidants, 2023 - mdpi.com
Globins have been studied for their “pseudo-peroxidase” activity for over 70 years, being an
ideal model of other kinetically more rapid metalloenzymes. Since those early days of globin …