MicroRNAs as important players in regulating cancer through PTEN/PI3K/AKT signalling pathways

SC Selvakumar, KA Preethi, D Sekar - Biochimica et Biophysica Acta (BBA) …, 2023 - Elsevier
Cancer being the leading cause of mortality has become a great threat worldwide. Current
cancer therapeutics lack specificity and have side effects due to a lack of understanding of …

Multiple myeloma: challenges encountered and future options for better treatment

S Das, N Juliana, NAA Yazit, S Azmani… - International Journal of …, 2022 - mdpi.com
Multiple myeloma (MM) is a malignant hematological disease. The disease is characterized
by the clonal proliferation of malignant plasma cells in the bone marrow. MM accounts for …

On maternity and the stronger immune response in women

E Mitchell, AL Graham, F Úbeda, G Wild - Nature communications, 2022 - nature.com
Medical research reports that women often exhibit stronger immune responses than men,
while pathogens tend to be more virulent in men. Current explanations cannot account for …

Computationally inferred cell-type specific epigenome-wide DNA methylation analysis unveils distinct methylation patterns among immune cells for HIV infection in …

X Zhang, Y Hu, RE Vandenhoudt, C Yan… - PLoS …, 2024 - journals.plos.org
Background Epigenome-wide association studies (EWAS) have identified CpG sites
associated with HIV infection in blood cells in bulk, which offer limited knowledge of cell-type …

Role of Nidogen-2 in diagnosis and prognosis of head and neck squamous cell carcinoma: a systematic review

TJ Chettiankandy, SS Sachdev… - Journal of Oral and …, 2022 - journals.lww.com
Materials and Methods: A systematic search was performed across multiple databases to
identify studies pertaining to analysis of expression or methylation of NID-2 in HNSCCs. The …

Epigenetic Changes Induced by Infectious Agents in Cancer

FE Tristan-Flores, C de la Rocha… - … Associated with the …, 2024 - Springer
Epigenetic abnormalities play a major role in the development and progression of several
types of human cancer. It is known that infectious agents can cause cancer via epigenetic …

DNA methylation profiles in urothelial bladder cancer tissues and children with schistosomiasis from Eggua, Ogun State, Nigeria

CA Akpabio, RP Ebuh, OE Fatunla, HO Awobode… - African Journal of …, 2023 - Springer
Background Squamous cell carcinoma has been attributed to chronic schistosomiasis and is
the predominant type of bladder cancer in schistosomiasis endemic areas. The aim of this …

Cell-type specific EWAS identifies genes involved in HIV pathogenesis and oncogenesis among people with HIV infection

X Zhang, Y Hu, RE Vandenhoudt, C Yan, VC Marconi… - bioRxiv, 2023 - biorxiv.org
Epigenome-wide association studies (EWAS) of heterogenous blood cells have identified
CpG sites associated with chronic HIV infection, which offer limited knowledge of cell-type …