The extracellular matrix (ECM) and integrins collaborate to regulate gene expression
associated with cell growth, differentiation and survival. Biochemical and molecular …

Syndecans function as membrane receptors for a bewildering array of ligands through their
glycosaminoglycan chains but their precise roles have been hard to pin down. Syndecans …

Adhesion of human primary skin fibroblasts and ECV304 endothelial cells to immobilized
matrix proteins, β1 or αv integrin antibodies stimulates tyrosine phosphorylation of the …

Integrins contribute to cell growth by providing a physical linkage between cytoskeletal
structures and the extracellular matrix, and also by participating in various signal …

Interactions of cells with the extracellular matrix are essential for the control of tissue
remodelling, cell migration, and embryogenesis. At the cell–extracellular matrix contact …

Protein kinase C (PKC) isoforms are central components in intracellular networks that
regulate a vast number of cellular processes. It has long been known that in most cell types …

The migration of endothelial cells (ECs) plays an important role in vascular remodeling and
regeneration. EC migration can be regulated by different mechanisms such as chemotaxis …

▪ Abstract Cell motility is an essential cellular process for a variety of biological events. The
process of cell migration requires the integration and coordination of complex biochemical …

Cell adhesion to extracellular matrix involves signaling mechanisms which control
attachment, spreading and the formation of focal adhesions and stress fibers. Fibronectin …

Two groups have now reported the viability of mice that lack syndecan-4. These mice have
wound healing/angiogenesis problems, and fibroblasts from these animals differ in …