Protein folding in vivo is mediated by an array of proteins that act either as 'foldases' or
'molecular chaperones'. Foldases include protein disulfide isomerase and peptidyl prolyl …

Two sequence‐unrelated families of proteins possess peptidylproline cis‐trans‐isomerase
activities (PPlase). PPlases are highly sequence conserved and multifunctional proteins …

The molecular mechanisms underlying the initiation and maintenance of the embryonic
pathway in plants are largely unknown. To obtain more insight into these processes, we …

Possible target proteins of chloroplast thioredoxin (Trx) have been investigated in the stroma
lysate of spinach chloroplasts. For that purpose, we immobilized a mutant of m-type Trx in …

Abstract Changes in the conformation of the units within the peptide chain are the
elementary processes in the folding of a protein into its native three‐dimensional structure …

Database searching has allowed the identification of a number of previously unreported
single and multidomain isoform members of the Arabidopsis cyclophilin gene family. In …

Cyclosporin A, the major immunosuppressive drug in transplantation, and the more potent
therapeutic drug candidate, FK506, have led to the discovery of two superfamilies of …

[Frontiers in Bioscience 9, 3453-3478, September 1, 2004] 3453 INSIGHTS INTO THE
CATALYTIC MECHANISM OF PEPTIDYL PROLYL CIS/TRAN Page 1 [Frontiers in …

Immunophilins are defined as receptors for immunosuppressive drugs including cyclosporin
A, FK506, and rapamycin. The cyclosporin A receptors are referred to as cyclophilins (CYPs) …

Cyclophilins constitute a subgroup of large family of proteins called immunophilins, which
also include FKBPs and Parvulins. They are remarkably conserved in all genera …