Peste des petits ruminants virus infection of small ruminants: a comprehensive review

N Kumar, S Maherchandani, SK Kashyap, SV Singh… - Viruses, 2014 - mdpi.com
Peste des petits ruminants (PPR) is caused by a Morbillivirus that belongs to the family
Paramyxoviridae. PPR is an acute, highly contagious and fatal disease primarily affecting …

Structure-based antigen design: a strategy for next generation vaccines

PR Dormitzer, JB Ulmer, R Rappuoli - Trends in biotechnology, 2008 - cell.com
Vaccine design is progressing from empiricism towards the increasingly rational
presentation of the targets of protective immunity. Nevertheless, most current vaccine …

Structure-based design of a soluble human cytomegalovirus glycoprotein B antigen stabilized in a prefusion-like conformation

MR Sponholtz, PO Byrne, AG Lee… - Proceedings of the …, 2024 - pnas.org
Human cytomegalovirus (HCMV) glycoprotein B (gB) is a class III membrane fusion protein
required for viral entry. HCMV vaccine candidates containing gB have demonstrated …

An antibody against the F glycoprotein inhibits Nipah and Hendra virus infections

HV Dang, YP Chan, YJ Park, J Snijder… - Nature structural & …, 2019 - nature.com
Abstract Nipah virus (NiV) and Hendra virus (HeV) are zoonotic henipaviruses (HNVs)
responsible for outbreaks of encephalitis and respiratory illness with fatality rates of 50 …

[HTML][HTML] Timing is everything: Fine-tuned molecular machines orchestrate paramyxovirus entry

S Bose, TS Jardetzky, RA Lamb - Virology, 2015 - Elsevier
The Paramyxoviridae include some of the great and ubiquitous disease-causing viruses of
humans and animals. In most paramyxoviruses, two viral membrane glycoproteins, fusion …

The respiratory syncytial virus fusion protein and neutrophils mediate the airway mucin response to pathogenic respiratory syncytial virus infection

KL Stokes, MG Currier, K Sakamoto, S Lee… - Journal of …, 2013 - Am Soc Microbiol
Respiratory syncytial virus (RSV) is the leading cause of death due to a viral etiology in
infants. RSV disease is characterized by epithelial desquamation, neutrophilic bronchiolitis …

Structures of the prefusion form of measles virus fusion protein in complex with inhibitors

T Hashiguchi, Y Fukuda, R Matsuoka… - Proceedings of the …, 2018 - National Acad Sciences
Measles virus (MeV), a major cause of childhood morbidity and mortality, is highly
immunotropic and one of the most contagious pathogens. MeV may establish, albeit rarely …

Structure and stabilization of the Hendra virus F glycoprotein in its prefusion form

JJW Wong, RG Paterson, RA Lamb… - Proceedings of the …, 2016 - National Acad Sciences
Hendra virus (HeV) is one of the two prototypical members of the Henipavirus genus of
paramyxoviruses, which are designated biosafety level 4 (BSL-4) organisms due to the high …

[HTML][HTML] Structure of the Newcastle disease virus F protein in the post-fusion conformation

K Swanson, X Wen, GP Leser, RG Paterson, RA Lamb… - Virology, 2010 - Elsevier
The paramyxovirus F protein is a class I viral membrane fusion protein which undergoes a
significant refolding transition during virus entry. Previous studies of the Newcastle disease …

Structural and mechanistic studies of measles virus illuminate paramyxovirus entry

RK Plemper, MA Brindley, RM Iorio - PLoS pathogens, 2011 - journals.plos.org
Measles virus (MeV), a member of the paramyxovirus family of enveloped RNA viruses and
one of the most infectious viral pathogens identified, accounts for major pediatric morbidity …