Background Traditionally, renal function in critically ill patients has been assessed to identify
renal dysfunction, and dose adjustment is generally accepted in such a context …

Augmented renal clearance (ARC) is a phenomenon in critically ill patients characterized by
increased creatinine clearance and elimination of renally eliminated medications. Patients …

Augmented renal clearance (ARC) has been reported in approximately 30–65% of patients
in the intensive care unit (ICU) despite the presence of a normal serum creatinine …

Highlights•Augmented renal clearance (ARC) is a prevalent condition in the critically
ill.•ARC may result in sub-therapeutic exposure of renally eliminated antibiotics.•Beta …

Kidney function assessment in the critically ill overlooks the possibility for hyperfunctioning
kidneys, known as augmented renal clearance (ARC), which could contribute to therapeutic …

Many critically ill patients display a supraphysiological renal function with enhanced renal
perfusion and glomerular hyperfiltration. This phenomenon described as augmented renal …

BACKGROUND Augmented renal clearance (ARC) is common in trauma patients and
associated with subtherapeutic antimicrobial concentrations. This study reported the …

Background: Augmented renal clearance (ARC) has frequently been observed in critically ill
patients. The risk factors for ARC in patients, including those in the general ward, and their …

Augmented renal clearance is commonly observed in septic patients and may result in
insufficient β-lactam serum concentrations. The aims of this study were to evaluate potential …

Vancomycin is a hydrophilic antibiotic widely used in severe infections, including bacteremia
and central nervous system (CNS) infections caused by Gram-positive bacteria such as …