The human obesity gene map: the 2005 update
T Rankinen, A Zuberi, YC Chagnon, SJ Weisnagel… - …, 2006 - Wiley Online Library
This paper presents the 12th update of the human obesity gene map, which incorporates
published results up to the end of October 2005. Evidence from single‐gene mutation …
published results up to the end of October 2005. Evidence from single‐gene mutation …
A promising therapeutic target for metabolic diseases: neuropeptide Y receptors in humans
Human neuropeptide Y (hNPY) is one of the most widely expressed neurotransmitters in the
human central and peripheral nervous systems. It consists of 36 highly conserved amino …
human central and peripheral nervous systems. It consists of 36 highly conserved amino …
The south pole telescope
A new 10 meter diameter telescope is being constructed for deployment at the NSF South
Pole research station. The telescope is designed for conducting large-area millimeter and …
Pole research station. The telescope is designed for conducting large-area millimeter and …
[图书][B] The evolution of obesity
ML Power, J Schulkin - 2009 - books.google.com
In this sweeping exploration of the relatively recent obesity epidemic, Michael L. Power and
Jay Schulkin probe evolutionary biology, history, physiology, and medical science to …
Jay Schulkin probe evolutionary biology, history, physiology, and medical science to …
The neuropeptide Y system: pathophysiological and therapeutic implications in obesity and cancer
L Zhang, MS Bijker, H Herzog - Pharmacology & therapeutics, 2011 - Elsevier
The neuropeptide Y (NPY) system–comprising of neuropeptide Y, peptide YY, pancreatic
polypeptide and the corresponding Y receptors through which they act (Y1, Y2, Y4, Y5 and …
polypeptide and the corresponding Y receptors through which they act (Y1, Y2, Y4, Y5 and …
Medical sequencing at the extremes of human body mass
N Ahituv, N Kavaslar, W Schackwitz… - The American Journal of …, 2007 - cell.com
Body weight is a quantitative trait with significant heritability in humans. To identify potential
genetic contributors to this phenotype, we resequenced the coding exons and splice …
genetic contributors to this phenotype, we resequenced the coding exons and splice …
Peptide YY is a regulator of energy homeostasis in obese children before and after weight loss
Context: The gut hormone peptide YY3–36 (PYY) reduces food intake via hypothalamic Y2
receptors in the brain. There is not much known about PYY in obese children. Objective: The …
receptors in the brain. There is not much known about PYY in obese children. Objective: The …
Powerful Bivariate Genome-Wide Association Analyses Suggest the SOX6 Gene Influencing Both Obesity and Osteoporosis Phenotypes in Males
Background Current genome-wide association studies (GWAS) are normally implemented in
a univariate framework and analyze different phenotypes in isolation. This univariate …
a univariate framework and analyze different phenotypes in isolation. This univariate …
Gastrointestinal morbidity in obesity
A Acosta, M Camilleri - Annals of the New York Academy of …, 2014 - Wiley Online Library
Obesity is a complex disease that results from increased energy intake and decreased
energy expenditure. The gastrointestinal system plays a key role in the pathogenesis of …
energy expenditure. The gastrointestinal system plays a key role in the pathogenesis of …
Association of SIRT1 gene variation with visceral obesity
AV Peeters, S Beckers, A Verrijken, I Mertens… - Human genetics, 2008 - Springer
The sirtuin SIRT1 is an important regulator of energy metabolism through its impact on
glucose and lipid metabolism and therefore we tested the hypothesis that genetic variation …
glucose and lipid metabolism and therefore we tested the hypothesis that genetic variation …