Ischemia and reperfusion injury in kidney transplantation: relevant mechanisms in injury and repair

GJ Nieuwenhuijs-Moeke, SE Pischke… - Journal of clinical …, 2020 - mdpi.com
Ischemia and reperfusion injury (IRI) is a complex pathophysiological phenomenon,
inevitable in kidney transplantation and one of the most important mechanisms for non-or …

Current and novel therapeutic approaches for treatment of neovascular age-related macular degeneration

RH ElSheikh, MZ Chauhan, AB Sallam - Biomolecules, 2022 - mdpi.com
Age-related macular degeneration AMD is one of the leading causes of blindness in the
elderly population. An advanced form of AMD known as neovascular AMD (nAMD) is …

[HTML][HTML] Cinnamaldehyde accelerates wound healing by promoting angiogenesis via up-regulation of PI3K and MAPK signaling pathways

X Yuan, L Han, P Fu, H Zeng, C Lv, W Chang… - Laboratory …, 2018 - Elsevier
The bark of Cinnamomum cassia (C. cassia) has been used for the management of coronary
heart disease (CHD) and diabetes mellitus. C. cassia may target the vasculature, as it …

Vascular endothelial growth factor in eye disease

JS Penn, A Madan, RB Caldwell, M Bartoli… - Progress in retinal and …, 2008 - Elsevier
Collectively, angiogenic ocular conditions represent the leading cause of irreversible vision
loss in developed countries. In the US, for example, retinopathy of prematurity, diabetic …

Diabetic macular edema: new concepts in patho-physiology and treatment

X Zhang, H Zeng, S Bao, N Wang, MC Gillies - Cell & bioscience, 2014 - Springer
Diabetic macular edema (DME), a serious eye complication caused primarily by
hyperglycemia, is one of the major causes of blindness. DME, which is characterized by …

[PDF][PDF] Renal cell carcinoma: Review of etiology, pathophysiology and risk factors.

N Petejova, A Martinek - … Papers of the Medical Faculty of …, 2016 - biomed.papers.upol.cz
Methods. A literature search using the databases Medscape, Pubmed, UpToDate and
EBSCO from 1945 to 2015. Results and Conclusions. Genetic predisposition/hereditary …

Renal Cell Carcinoma: Dynamic Contrast-enhanced MR Imaging for Differentiation of Tumor Subtypes—Correlation with Pathologic Findings1

MRM Sun, L Ngo, EM Genega, MB Atkins, ME Finn… - Radiology, 2009 - pubs.rsna.org
Purpose: To retrospectively evaluate whether the enhancement patterns of pathologically
proved clear cell, papillary, and chromophobe renal cell carcinomas (RCCs) measured on …

Unraveling a multifactorial late-onset disease: from genetic susceptibility to disease mechanisms for age-related macular degeneration

A Swaroop, EY Chew, C Bowes Rickman… - Annual review of …, 2009 - annualreviews.org
Aging-associated neurodegenerative diseases significantly influence the quality of life of
affected individuals. Genetic approaches, combined with genomic technology, have …

Limiting angiogenesis to modulate scar formation

S Korntner, C Lehner, R Gehwolf, A Wagner… - Advanced Drug Delivery …, 2019 - Elsevier
Angiogenesis, the process of new blood vessel formation from existing blood vessels, is a
key aspect of virtually every repair process. During wound healing an extensive, but …

Hypoxia inducible factor 1-alpha (HIF-1 alpha) is induced during reperfusion after renal ischemia and is critical for proximal tubule cell survival

E Conde, L Alegre, I Blanco-Sanchez… - PloS one, 2012 - journals.plos.org
Acute tubular necrosis (ATN) caused by ischemia/reperfusion (I/R) during renal
transplantation delays allograft function. Identification of factors that mediate protection …