Eighty percent of all malignant primary brain tumors diagnosed in the United States are
gliomas. 1 The current treatment paradigm for high-grade gliomas (grades III and IV) …

Somatic mutations of genes involved in NF-κB, PI3K/AKT, NOTCH, and JAK/STAT signaling
pathways play an important role in the pathogenesis of Hodgkin lymphoma (HL). HL tumor …

The accurate identification of glioblastoma progression remains an unmet clinical need. The
aim of this prospective single-institutional study is to determine and validate thresholds for …

The aim of this study is to present the 5-year relative survival by stage of breast and
colorectal cancer patients in a northern Italian province. For the period 2013-2015, cases …

Background Population aging is a common demographic pattern in developed countries,
and aging increases the risk of cancer. The disproportionately high cancer burden, as a …

Objective: Tissue inhibitor of metalloproteinases 1 (TIMP-1) and matrix metalloproteinase 7
(MMP-7) were reported to have potent growth promoting activity. Lack of balance between …

Genetic variations in 3′ untranslated regions of target genes may affect microRNA binding,
resulting in differential protein expression. microRNAs regulate DNA repair, and single …

Colorectal cancer (CRC) is the second leading tumor diagnosis in women and men in the
Czech Republic. Patient outcome depends on tumor stage at the time of diagnosis and, in …

Clear-cell renal cell carcinomas (ccRCCs) are genetically heterogeneous tumors presenting
diverse clinical courses. Epithelial-mesenchymal transition (EMT) is a crucial process …

Background: The primary objective of this study was to investigate the impact of high protein
oral nutrition support (ONS) on clinical outcomes in patients with colorectal cancer (CRC) …