All implanted biomaterials are targets of the host's immune system. While the host
inflammatory response was once considered a detrimental force to be blunted or avoided, in …

The immune system not only acts as a defense against pathogen and cancer cells, but also
plays an important role in homeostasis and tissue regeneration. Targeting immune systems …

Extracellular vesicles (EVs) are potential alternatives for mesenchymal stem cells (MSCs) in
the treatment of musculoskeletal degenerative diseases, including intervertebral disc …

Control of inflammation is indispensable for optimal oral wound healing and tissue
regeneration. Several biomaterials have been used to enhance the regenerative outcomes; …

Alginate biopolymers are characterized by favorable properties, of biocompatibility,
degradability, and non-toxicity. However, the poor stability properties of alginate have limited …

Considering the high prevalence and the complex pharmacological management of immune-
mediated inflammatory diseases (IMIDs), the search for new therapeutic approaches for their …

The interrogation of single cells has revolutionised biology and medicine by providing
crucial unparalleled insights into cell-to-cell heterogeneity. Flow cytometry (including …

Inflammation plays a central role in wound healing following injury or disease and is
mediated by a precise cascade of cellular and molecular events. Unresolved inflammatory …

Cancer immunotherapy, which reprograms a patient's own immune system to eradicate
cancer cells, has been demonstrated as a promising therapeutic strategy clinically. Immune …

The extracellular matrix (ECM) mechanical properties regulate key cellular processes in
tissue development and regeneration. The majority of scientific investigation has focused on …