Polycyclic polyprenylated acylphloroglucinols (PPAPs) are a class of hybrid natural products
sharing the mevalonate/methylerythritol phosphate and polyketide biosynthetic pathways …

Alzheimer's disease (AD) is the most common type of dementia and is characterized by the
accumulation of amyloid (Aβ) plaques and neurofibrillary tangles in the brain. Much attention …

The large Trp gene family encodes transient receptor potential (TRP) proteins that form
novel cation-selective ion channels. In mammals, 28 Trp channel genes have been …

Alzheimer's disease (AD) is a frequent and disabling neurodegenerative disorder, in which
astrocytes participate in several pathophysiological processes including neuroinflammation …

When we edited in 2007 the first issue on transient receptor potential channel in the
Handbook of Experimental Pharmacology, we were all very excited by the progress in this …

Peering into the field of Alzheimer's disease (AD), the outsider realizes that many of the
therapeutic strategies tested (in animal models) have been successful. One also may notice …

Hypericum perforatum (HP) belongs to the Hypericaceae family and is one of the oldest
used and most extensively investigated medicinal herbs. The medicinal form comprises the …

Acetylcholinesterase (AChE; EC 3.1. 1.7) plays a crucial role in the rapid hydrolysis of the
neurotransmitter acetylcholine, in the central and peripheral nervous system and might also …

Four new δ-and γ-lactone derivatives, hyperelatolides A–D (1–4, respectively), were
discovered from the aerial portions of Hypericum elatoides R. Keller. Their structures were …

Abstract Hypericum perforatum L.(Clusiaceae), commonly known as St. John's wort, has a
rich historical background as one of the oldest and most widely studied herbal medicines …