Immunopathogenesis of systemic lupus erythematosus: an update

L Arnaud, F Chasset, T Martin - Autoimmunity Reviews, 2024 - Elsevier
Systemic lupus erythematosus (SLE) is a chronic systemic autoimmune disease
characterized by dysregulated immune responses leading to widespread inflammation and …

Platelets are a major player and represent a therapeutic opportunity in systemic lupus erythematosus

M Robert, M Scherlinger - Joint Bone Spine, 2024 - Elsevier
Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by immune
dysregulation and organ injury with a premature mortality due to cardiovascular diseases …

Alternative platelet differentiation pathways initiated by nonhierarchically related hematopoietic stem cells

J Carrelha, S Mazzi, A Winroth… - Nature …, 2024 - nature.com
Rare multipotent stem cells replenish millions of blood cells per second through a time-
consuming process, passing through multiple stages of increasingly lineage-restricted …

Identification of platelet-related subtypes and diagnostic markers in pediatric Crohn's disease based on WGCNA and machine learning

D Tang, Y Huang, Y Che, C Yang, B Pu, S Liu… - Frontiers in …, 2024 - frontiersin.org
Background The incidence of pediatric Crohn's disease (PCD) is increasing worldwide
every year. The challenges in early diagnosis and treatment of PCD persist due to its …

Platelet activation through CD62P and the formation of platelet–monocyte complexes are associated with the exacerbation of mucosal inflammation in patients with …

Y Sano, T Tomiyama, N Yagi, Y Ito, Y Honzawa… - Scientific Reports, 2024 - nature.com
Ulcerative colitis (UC) is a refractory, chronic inflammatory bowel disease of unknown
etiology. Although platelets are activated in UC, their relevance in pathophysiology remains …

Impaired bisecting GlcNAc reprogrammed M1 polarization of macrophage

X He, B Wang, W Deng, J Cao, Z Tan, X Li… - Cell Communication and …, 2024 - Springer
The functions of macrophages are governed by distinct polarization phenotypes, which can
be categorized as either anti-tumor/M1 type or pro-tumor/M2 type. Glycosylation is known to …

Molecular intersections of traumatic brain injury and Alzheimer's disease: the role of ADMSC-derived exosomes and hub genes in microglial polarization

P Li, L Ye, S Sun, Y Wang, Y Chen, J Chang… - Metabolic Brain …, 2025 - Springer
Traumatic brain injury (TBI) is a significant contributor to global mortality and morbidity, with
emerging evidence indicating a heightened risk of developing Alzheimer's disease (AD) …

Clinical Significance of Abnormal Serum LGALS3BP Expression in Patients with Idiopathic Inflammatory Myopathies

L Huang, X Huang, W Zhou, Y Jiang… - Journal of …, 2024 - Taylor & Francis
Objective Idiopathic inflammatory myopathies (IIM) are classified into four subgroups:
dermatomyositis (DM), anti-synthetase syndrome (ASS), immune-mediated necrotizing …

Biomarkers for systemic lupus erythematosus: A scoping review

S Zhang, R Xu, L Kang - Immunity, Inflammation and Disease, 2024 - Wiley Online Library
Background In recent years, newly discovered potential biomarkers have great research
potential in the diagnosis, disease activity prediction, and treatment of systemic lupus …

Predictive Value of Combined Detection of Serum LGALS3BP and GDF-15 for the Prognosis of ICU Sepsis Patients

D Ji, J Li, A Liu, R Ye, S Zhang, L Gao… - Infection and Drug …, 2024 - Taylor & Francis
Objective This study aims to investigate the effectiveness of combining serum lectin
galactoside-binding soluble 3 binding protein (LGALS3BP) with growth differentiation factor …