Plasmodium parasites, the causative agents of malaria, have developed elaborate
strategies that they use to survive and thrive within different intracellular environments …

Phylum Apicomplexa comprises a large group of obligate intracellular parasites of high
medical and veterinary importance. These organisms succeed intracellularly by effecting …

The most severe form of human malaria is caused by Plasmodium falciparum. Its virulence is
closely linked to the increase in rigidity of infected erythrocytes and their adhesion to …

Malaria remains a heavy public health and socioeconomic burden in tropical and
subtropical regions. Increasing resistance against front-line treatments implies that novel …

Recent progress in reducing malaria cases and ensuing deaths is threatened by factors like
mutations that induce resistance to artemisinin derivatives. Multiple drugs are currently in …

Malaria elimination is still pending on the development of novel tools that rely on a deep
understanding of parasite biology. Proteins of all living cells undergo myriad …

Repetitive low complexity sequences, mostly assumed to have no function, are common in
proteins that are exported by the malaria parasite into its host erythrocyte. We identify a …

Malaria control relies heavily on the small number of existing antimalarial drugs. However,
recurring antimalarial drug resistance necessitates the continual generation of new …

A relatively high-affinity inhibitor of FIKK kinase from the malaria parasite Plasmodium vivax
was identified by in vitro assay of recombinant kinase. The FIKK kinase family is unique to …

The high prevalence of sickle cell disease in some human populations likely results from the
protection afforded against severe Plasmodium falciparum malaria and death by …