Oligodendrocyte precursor cells (OPCs) account for 5% of the resident parenchymal central
nervous system glial cells. OPCs are not only a back-up for the loss of oligodendrocytes that …

Neurodegenerative diseases including Alzheimer's disease and Parkinson's disease are
aging‐associated diseases with irreversible damage of brain tissue. Oxidative stress is …

In 2008, we published the first set of guidelines for standardizing research in autophagy.
Since then, this topic has received increasing attention, and many scientists have entered …

MicroRNAs are post-transcriptional regulators of gene expression, crucial for neuronal
differentiation, survival, and activity. Age-related dysregulation of microRNA biogenesis …

Reactive oxygen species (ROS) are important molecules in the living organisms as a part of
many signaling pathways. However, if overproduced, they also play a significant role in the …

Vitamin E (alpha-tocopherol) is an essential micronutrient and fat-soluble antioxidant with
proposed role in protecting tissues from uncontrolled lipid peroxidation. This vitamin has …

Multi-pathway approaches for the treatment of complex polygenic disorders are emerging as
alternatives to classical monotarget therapies and microRNAs are of particular interest in …

Nonalcoholic fatty liver disease (NAFLD), or, more accurately, metabolic associated fatty
liver disease, accounts for a large proportion of chronic liver disorders worldwide and is …

MicroRNAs (miRNAs) are small RNAs that do not encode for proteins and play key roles in
the regulation of gene expression. miRNAs are involved in a comprehensive range of …

Imbalanced regulation of reactive oxygen species (ROS) and antioxidant factors in cells is
known as “oxidative stress (OS)”. OS regulates key cellular physiological responses through …