Atherosclerosis is the main risk factor for cardiovascular disease (CVD), which is the leading
cause of mortality worldwide. Atherosclerosis is initiated by endothelium activation and …

Epigenetics is closely related to cardiovascular diseases. Genome-wide linkage and
association analyses and candidate gene approaches illustrate the multigenic complexity of …

Cholesterol homeostasis is vital for proper cellular and systemic functions. Disturbed
cholesterol balance underlies not only cardiovascular disease but also an increasing …

Recent advances have highlighted the ability of hematopoietic stem and progenitor cells in
the bone marrow to sense peripheral inflammation or infection and adapt through increased …

Evidence accumulated over the past decade has verified that long non-coding RNAs
(lncRNAs) exert important functions in multiple cell programs. As a novel class of cellular …

The mechanisms underlying sterol transport in mammalian cells are poorly understood. In
particular, how cholesterol internalized from HDL is made available to the cell for storage or …

Atherosclerosis underlies the predominant number of cardiovascular diseases and remains
a leading cause of morbidity and mortality worldwide. The development, progression and …

Atherosclerosis is one of the primary causes of cardiovascular disease and mortality. This
chronic immunometabolic disease evolves during decades in humans and encompasses …

Altered metabolic patterns in tumor cells not only meet their own growth requirements but
also shape an immunosuppressive microenvironment through multiple mechanisms …

Atherosclerotic cardio-cerebrovascular disease and death remain the leading cause of
morbidity and mortality worldwide. Defective efferocytosis, the clearance of apoptotic cells by …