Microtubule specialization by+ TIP networks: from mechanisms to functional implications
SM Meier, MO Steinmetz, Y Barral - Trends in Biochemical Sciences, 2024 - cell.com
To fulfill their actual cellular role, individual microtubules become functionally specialized
through a broad range of mechanisms. The 'search and capture'model posits that …
through a broad range of mechanisms. The 'search and capture'model posits that …
TOR Complex 1: Orchestrating Nutrient Signaling and Cell Cycle Progression
M Foltman, A Sanchez-Diaz - International Journal of Molecular Sciences, 2023 - mdpi.com
The highly conserved TOR signaling pathway is crucial for coordinating cellular growth with
the cell cycle machinery in eukaryotes. One of the two TOR complexes in budding yeast …
the cell cycle machinery in eukaryotes. One of the two TOR complexes in budding yeast …
Phase separation of a microtubule plus-end tracking protein into a fluid fractal network
Microtubule plus-end tracking proteins (+ TIPs) participate in nearly all microtubule-based
cellular processes and have recently been proposed to function as liquid condensates …
cellular processes and have recently been proposed to function as liquid condensates …
In vitro reconstitution defines the mechanistic basis of HSET motor activity regulation by IntraFlagellar Transport proteins
A Guesdon, V Simon, J Van Dijk, B Delaval, B Vitre - bioRxiv, 2025 - biorxiv.org
HSET is a mitotic kinesin essential for centrosome clustering in cells harboring
supernumerary centrosomes. Previous work in cellulo revealed a physical and functional …
supernumerary centrosomes. Previous work in cellulo revealed a physical and functional …