Chlorogenic acid: A comprehensive review of the dietary sources, processing effects, bioavailability, beneficial properties, mechanisms of action, and future directions

H Lu, Z Tian, Y Cui, Z Liu, X Ma - Comprehensive reviews in …, 2020 - Wiley Online Library
Chlorogenic acids (CGAs), a group of hydroxycinnamates, are generally abundant in
everyday foods and beverages, most prominently in certain coffee drinks. Among them, the …

Natural sources, pharmacokinetics, biological activities and health benefits of hydroxycinnamic acids and their metabolites

M Sova, L Saso - Nutrients, 2020 - mdpi.com
Hydroxycinnamic acids (HCAs) are important natural phenolic compounds present in high
concentrations in fruits, vegetables, cereals, coffee, tea and wine. Many health beneficial …

Apple phenolic extracts ameliorate lead-induced cognitive impairment and depression-and anxiety-like behavior in mice by abating oxidative stress, inflammation and …

Y Ren, D Sun-Waterhouse, F Ouyang, X Tan, D Li… - Food & function, 2022 - pubs.rsc.org
Lead can lead to neurotoxicity and cognitive impairment. In this study, for the first time, the
protective effects and working mechanisms of apple phenolic extracts (APEs) against lead …

Effect of chlorogenic acid supplementation in MPTP-intoxicated mouse

SS Singh, SN Rai, H Birla, W Zahra, G Kumar… - Frontiers in …, 2018 - frontiersin.org
Oxidative stress and neuroinflammation play a key role in dopaminergic (DA) neuronal
degeneration, which results in the hindrance of normal ongoing biological processes in the …

[HTML][HTML] Recent advances and possibilities for the use of plant phenolic compounds to manage ageing-related diseases

HS Arruda, IA Neri-Numa, LA Kido, MRM Júnior… - Journal of Functional …, 2020 - Elsevier
Ageing is an emerging global public health concern due to the increasing number of elderly
people and ageing-related degenerative disorders. Given the absence of effective …

Neuroprotective Potential of Mung Bean (Vigna radiata L.) Polyphenols in Alzheimer's Disease: A Review

H Xu, Q Zhou, B Liu, KW Cheng, F Chen… - Journal of Agricultural …, 2021 - ACS Publications
Mung bean contains various neuroprotective polyphenols, so it might be a healthy food for
Alzheimer's disease (AD) prevention. Totally, 19 major phenolic compounds were quantified …

Neuroprotective effect of chlorogenic acid in global cerebral ischemia-reperfusion rat model

G Kumar, S Mukherjee, P Paliwal, SS Singh… - Naunyn-Schmiedeberg's …, 2019 - Springer
The ischemic cascade is initiated in the hypoperfused region of the brain that leads to
neuronal cell death. Identification of multi-target inhibitor against prominent molecular …

Comparative metabolism study on chlorogenic acid, cryptochlorogenic acid and neochlorogenic acid using UHPLC-Q-TOF MS coupled with network pharmacology

LI Jie, W Shao-Ping, W Yu-Qi, SHI Lei, ZK Zhang… - Chinese Journal of …, 2021 - Elsevier
Abstract Chlorogenic acid (5-CQA), neochlorogenic acid (3-CQA), and cryptochlorogenic
acid (4-CQA), usually simultaneously exist in many traditional Chinese medicines (TCMs) …

Erythronium japonicum Alleviates Inflammatory Pain by Inhibiting MAPK Activation and by Suppressing NF-κB Activation via ERK/Nrf2/HO-1 Signaling Pathway

J Park, YT Kim - Antioxidants, 2020 - mdpi.com
Microglial activation-mediated neuroinflammation influences the development of
inflammatory pain. The aim of this study was to investigate the anti-inflammatory effects and …

Attenuation of palmitic acid–induced lipotoxicity by chlorogenic acid through activation of SIRT1 in hepatocytes

L Yang, J Wei, F Sheng, P Li - Molecular nutrition & food …, 2019 - Wiley Online Library
Scope Saturated free fatty acids (FFAs) induce hepatocyte lipotoxicity, wherein oxidative
stress–associated mitochondrial dysfunction is mechanistically involved. Chlorogenic acid …