The promise of circulating tumor DNA in head and neck cancer

SS Aulakh, DA Silverman, K Young, SK Dennis… - Cancers, 2022 - mdpi.com
Simple Summary Head and neck cancer remains a challenging and deadly disease as it is
often identified in more advanced stages due to limitations in screening and surveillance …

Mapping the Potential of Microfluidics in Early Diagnosis and Personalized Treatment of Head and Neck Cancers

S Pillai, JC Kwan, F Yaziji, H Yu, SD Tran - Cancers, 2023 - mdpi.com
Simple Summary Head and neck cancers (HNCs) are a group of cancers that affect parts
like the mouth, throat, and glands in the neck. These cancers are quite complex and can be …

Personalizing surveillance in head and neck cancer

GJ Hanna, N Patel, SG Tedla, KL Baugnon… - American Society of …, 2023 - ascopubs.org
Head and neck squamous cell carcinoma (HNSCC) encompasses a spectrum of
heterogeneous diseases originating in the oral cavity, pharynx, and larynx. Within the United …

Emerging roles of circulating tumor DNA for increased precision and personalization in radiation oncology

N Earland, K Chen, NP Semenkovich… - Seminars in Radiation …, 2023 - Elsevier
Recent breakthroughs in circulating tumor DNA (ctDNA) technologies present a compelling
opportunity to combine this emerging liquid biopsy approach with the field of radiogenomics …

Liquid biopsy in head and neck cancer: current evidence and future perspective on squamous cell, salivary gland, paranasal sinus and nasopharyngeal cancers

S Cabezas-Camarero, P Pérez-Segura - Cancers, 2022 - mdpi.com
Simple Summary Head and neck cancer is the sixth most common type of solid tumor and
harbors a poor prognosis since most patients are diagnosed at an advanced stage. The …

Blood plasma exosomes contain circulating DNA in their crown

O Tutanov, T Shtam, A Grigor'eva, A Tupikin… - Diagnostics, 2022 - mdpi.com
It is known that circulating DNA (cirDNA) is protected from nuclease activity by proteins that
form macromolecular complexes with DNA. In addition, it was previously shown that cirDNA …

Circulating tumor DNA in head and neck squamous cell carcinoma: Association with metabolic tumor burden determined with FDG-PET/CT

A Silvoniemi, J Laine, K Aro, L Nissi, L Bäck, J Schildt… - Cancers, 2023 - mdpi.com
Simple Summary The detection of circulating tumor DNA (ctDNA) has gained increasing
interest in precision oncology. In head and neck squamous cell carcinoma (HNSCC), a …

Molecular pathways and targeted therapies in head and neck cancers pathogenesis

M Constantin, MC Chifiriuc, C Bleotu… - Frontiers in …, 2024 - pmc.ncbi.nlm.nih.gov
The substantial heterogeneity exhibited by head and neck cancer (HNC), encompassing
diverse cellular origins, anatomical locations, and etiological contributors, combined with the …

SFPQ and Its Isoform as Potential Biomarker for Non-Small-Cell Lung Cancer

L Yang, A Gilbertsen, B Jacobson, J Pham… - International journal of …, 2023 - mdpi.com
Cancer markers are measurable molecules in the blood or tissue that are produced by tumor
cells or immune cells in response to cancer progression. They play an important role in …

Integrating cutting-edge methods to oral cancer screening, analysis, and prognosis

S Dholariya, RD Singh, A Sonagra… - Critical Reviews™ in …, 2023 - dl.begellhouse.com
Oral cancer (OC) has become a significant barrier to health worldwide due to its high
morbidity and mortality rates. OC is among the most prevalent types of cancer that affect the …