The burden of irreversible vision loss from Glaucoma continues to rise. While the disease
pathogenesis is not well understood, intraocular pressure (IOP) is the only modifiable risk …

Citicoline is the generic name of the pharmaceutical substance that chemically is cytidine-
5′-diphosphocholine (CDP-choline), which is identical to the natural intracellular precursor …

Glaucoma is a neurodegenerative disease characterized by progressive loss of retinal
ganglion cells and their axons. Lowering of intraocular pressure (IOP) is currently the only …

The cholinergic system has a crucial role to play in visual function. Although cholinergic
drugs have been a focus of attention as glaucoma medications for reducing eye pressure …

Abstract Ubiquitin Proteasome System (UPS) is an adaptable and finely tuned system that
sustains proteostasis network under a large variety of physiopathological conditions. Its …

This review is based on the previous one published in 2010–Secades JJ. Citicoline:
pharmacological and clinical review, 2010 update. Rev Neurol 2011; 52 (Suppl 2): S1-62 …

Glaucoma is an optic neuropathy, specifically a neurodegenerative disease characterized
by loss of retinal ganglion cells (RGCs) and their axons. The pathogenesis of RGC loss in …

Glaucoma, a leading cause of irreversible blindness worldwide, is an optic neuropathy
characterized by the progressive death of retinal ganglion cells (RGCs). Elevated intraocular …

Purpose To evaluate the retinal function and the neural conduction along the visual
pathways after treatment with citicoline eye drops in patients with open angle glaucoma …

This review is based on the previous one published in 2010–Secades JJ. Citicoline:
pharmacological and clinical review, 2010 update. Rev Neurol 2011; 52 (Suppl 2): S1-62 …