Background Lactoferrin, a normal component of human colostrum and milk, can enhance
host defenses and may be effective for prevention of sepsis and necrotizing enterocolitis …

Breast milk contains immunomodulating components that are beneficial to newborns during
maturation of their immune system. Human breast milk composition is influenced by an …

The COVID-19 pandemic is a serious global health threat caused by severe acute
respiratory syndrome of coronavirus 2 (SARS-CoV-2). Symptoms of COVID-19 are highly …

Necrotizing enterocolitis (NEC) is a severe gastrointestinal disease of the premature infant
with high mortality and morbidity. Children who survive NEC have been shown to …

Lactoferrin (Lf) is a glycoprotein present in human and bovine milk with antimicrobial and
immune-modulating properties. This review aimed to examine the evidence for the effect of …

As lactoferrin is a nutritional supplement with proven antiviral and immunomodulatory
abilities, it may be used to improve the clinical course of COVID-19. The clinical efficacy and …

Fetal and neonatal development represents a critical window for setting a path toward health
throughout life. In this review, we focus on intestinal immunity, how it develops, and its …

The gut microbiome plays an integral role in health and disease, and diet is a major driver of
its composition, diversity, and functional capacity. Given the dynamic development of the gut …

Multiple properties of lactoferrin have been reported in the literature so far. Decades of in
vitro and in vivo studies have demonstrated the important antimicrobial, anti-inflammatory …

Background Very low birthweight or preterm infants are at increased risk of adverse
outcomes including sepsis, necrotising enterocolitis, and death. We assessed whether …