SARS-CoV-2 ORF8: a rapidly evolving immune and viral modulator in COVID-19

A Arduini, F Laprise, C Liang - Viruses, 2023 - mdpi.com
The COVID-19 pandemic has resulted in upwards of 6.8 million deaths over the past three
years, and the frequent emergence of variants continues to strain global health. Although …

[HTML][HTML] SARS-CoV-2 disrupts host epigenetic regulation via histone mimicry

J Kee, S Thudium, DM Renner, K Glastad, K Palozola… - Nature, 2022 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged at the end of
2019 and caused the devastating global pandemic of coronavirus disease 2019 (COVID …

Enhanced inhibition of MHC-I expression by SARS-CoV-2 Omicron subvariants

M Moriyama, C Lucas, VS Monteiro… - Proceedings of the …, 2023 - National Acad Sciences
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs)
possess mutations that confer resistance to neutralizing antibodies within the Spike protein …

Early peripheral blood MCEMP1 and HLA-DRA expression predicts COVID-19 prognosis

KR Chan, CWT Koh, DHL Ng, S Qin, JSG Ooi… - …, 2023 - thelancet.com
Background Mass vaccination has dramatically reduced the incidence of severe COVID-19,
with most cases now presenting as self-limiting upper respiratory tract infections. However …

Exploration of blood− derived coding and non-coding RNA diagnostic immunological panels for COVID-19 through a co-expressed-based machine learning …

M Zarei Ghobadi, R Emamzadeh… - Frontiers in …, 2022 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative virus of the
pandemic coronavirus disease 2019 (COVID-19). Evaluating the immunological factors and …

Helminth antigens differentially modulate the activation of CD4+ and CD8+ T lymphocytes of convalescent COVID-19 patients in vitro

T Adjobimey, J Meyer, V Terkeš, M Parcina, A Hoerauf - BMC medicine, 2022 - Springer
Background The coronavirus disease 2019 (COVID-19) is a respiratory disease caused by
SARS-CoV-2, a recently discovered strain of coronavirus. The virus has spread rapidly …

SARS-CoV-2 Omicron subvariants evolved to promote further escape from MHC-I recognition

M Moriyama, C Lucas, VS Monteiro… - bioRxiv, 2022 - biorxiv.org
SARS-CoV-2 variants of concern (VOCs) possess mutations that confer resistance to
neutralizing antibodies within the Spike protein and are associated with breakthrough …

Heterologous booster vaccination with CoronaVac following prime vaccination with mRNA vaccine

YS Goh, SW Fong, A Rouers, ZW Chang… - Clinical & …, 2022 - Wiley Online Library
Objective Despite the high vaccine efficacy of mRNA COVID‐19 vaccines, there are
individuals who developed excessive reactogenic and/or allergic responses after the first …

Genomic and transcriptomic characterization of Delta SARS-CoV-2 infection in free-ranging white-tailed deer (Odocoileus virginianus)

JD Kotwa, B Lobb, A Massé, M Gagnier, P Aftanas… - Iscience, 2023 - cell.com
White-tailed deer (WTD) are susceptible to SARS-CoV-2 and represent an important species
for surveillance. Samples from WTD (n= 258) collected in November 2021 from Québec …

Filariasis research–from basic research to drug development and novel diagnostics, over a decade of research at the Institute for Medical Microbiology, Immunology …

I Karunakaran, M Ritter, K Pfarr… - Frontiers in tropical …, 2023 - frontiersin.org
Filariae are vector borne parasitic nematodes, endemic in tropical and subtropical regions
causing avoidable infections ranging from asymptomatic to stigmatizing and disfiguring …