Discovery of a Clinical Stage Multi-Kinase Inhibitor Sodium (E)-2-{2-Methoxy-5-[(2′,4′,6′-trimethoxystyrylsulfonyl)methyl]phenylamino}acetate (ON 01910.Na) …
MVR Reddy, P Venkatapuram… - Journal of medicinal …, 2011 - ACS Publications
Cyclin D proteins are elevated in many cancer cells, and targeted deletion of cyclin D1 gene
in the mammary tissues protects mice from breast cancer. Accordingly, there is an increasing …
in the mammary tissues protects mice from breast cancer. Accordingly, there is an increasing …
Design, Synthesis, and Biological Evaluation of (E)-Styrylbenzylsulfones as Novel Anticancer Agents
MVR Reddy, MR Mallireddigari… - Journal of medicinal …, 2008 - ACS Publications
Cell cycle progression is regulated by cyclins and cyclin-dependent kinases, which are
formed at specific stages of the cell cycle and regulate the G1/S and G2/M phase transitions …
formed at specific stages of the cell cycle and regulate the G1/S and G2/M phase transitions …
Synthesis of chlorovinyl sulfones as structural analogs of chalcones and their antiplasmodial activities
JN Dominguez, C Leon, J Rodrigues… - European journal of …, 2009 - Elsevier
The synthesis of novel chlorovinyl sulfone-like chalcone derivatives and their antimalarial
activity against cultured Plasmodium falciparum parasites, hemozoin formation, hemoglobin …
activity against cultured Plasmodium falciparum parasites, hemozoin formation, hemoglobin …
Design, Synthesis, and Biological Evaluation of (E)-N-Aryl-2-arylethenesulfonamide Analogues as Potent and Orally Bioavailable Microtubule-Targeted Anticancer …
MVR Reddy, MR Mallireddigari… - Journal of medicinal …, 2013 - ACS Publications
A series of novel (E)-N-aryl-2-arylethenesulfonamides (6) were synthesized and evaluated
for their anticancer activity. Some of the compounds in this series showed potent cytotoxicity …
for their anticancer activity. Some of the compounds in this series showed potent cytotoxicity …
Synthesis of polyhydroxylated derivatives of phenyl vinyl sulfone as structural analogs of chalcones
MT Konieczny, B Horowska, A Kunikowski… - …, 2001 - thieme-connect.com
A series of polyhydroxylated phenyl vinyl sulfones was prepared by phase transfer
condensation of suitable phenyl methyl sulfones with substituted benzaldehydes. The …
condensation of suitable phenyl methyl sulfones with substituted benzaldehydes. The …
Styryl sulfone anticancer agents
EP Reddy, MVR Reddy - US Patent 6,359,013, 2002 - Google Patents
US6359013B1 - Styryl sulfone anticancer agents - Google Patents US6359013B1 - Styryl
sulfone anticancer agents - Google Patents Styryl sulfone anticancer agents Download PDF …
sulfone anticancer agents - Google Patents Styryl sulfone anticancer agents Download PDF …
Substituted styryl benzylsulfones for treating proliferative disorders
EP Reddy, MVR Reddy - US Patent 6,486,210, 2002 - Google Patents
US6486210B2 - Substituted styryl benzylsulfones for treating proliferative disorders -
Google Patents US6486210B2 - Substituted styryl benzylsulfones for treating proliferative …
Google Patents US6486210B2 - Substituted styryl benzylsulfones for treating proliferative …
α, β-unsaturated sulfones for treating proliferative disorders
EP Reddy, MVR Reddy - US Patent 6,541,475, 2003 - Google Patents
US6541475B2 - α, β-unsaturated sulfones for treating proliferative disorders - Google Patents
US6541475B2 - α, β-unsaturated sulfones for treating proliferative disorders - Google Patents …
US6541475B2 - α, β-unsaturated sulfones for treating proliferative disorders - Google Patents …
Z-styryl sulfone anticancer agents
EP Reddy, MVR Reddy - US Patent 6,201,154, 2001 - Google Patents
Extracellular signals received at transmembrane receptors are relayed into the cells by the
Signal transduction pathways (Pelech et al., Science 257: 1335 (1992)) which have been …
Signal transduction pathways (Pelech et al., Science 257: 1335 (1992)) which have been …
Styryl sulfone anticancer agents
EP Reddy, MVR Reddy - US Patent 6,548,553, 2003 - Google Patents
US6548553B2 - Styryl sulfone anticancer agents - Google Patents US6548553B2 - Styryl
sulfone anticancer agents - Google Patents Styryl sulfone anticancer agents Download PDF Info …
sulfone anticancer agents - Google Patents Styryl sulfone anticancer agents Download PDF Info …