Media Matters, Examining Historical and Modern Streptococcus pneumoniae Growth Media and the Experiments They Affect

Y Sanchez-Rosario, MDL Johnson - Frontiers in Cellular and Infection …, 2021 - frontiersin.org
While some bacteria can thrive for generations in minerals and salts, many require lavish
nutrition and specific chemicals to survive to the point where they can be observed and …

Pneumococcal virulence factors in community-acquired pneumonia

C Feldman, R Anderson - Current opinion in pulmonary medicine, 2020 - journals.lww.com
Pneumococcal virulence factors in community-acquired pneumon... : Current Opinion in
Pulmonary Medicine Pneumococcal virulence factors in community-acquired pneumonia …

Difluoromethylornithine (DFMO) and AMXT 1501 inhibit capsule biosynthesis in pneumococci

MB Ayoola, LA Shack, JH Lee, J Lim, H Eoh… - Scientific Reports, 2022 - nature.com
Polyamines are small cationic molecules that have been linked to various cellular processes
including replication, translation, stress response and recently, capsule regulation in …

Polyamine Synthesis Effects Capsule Expression by Reduction of Precursors in Streptococcus pneumoniae

MB Ayoola, LA Shack, MF Nakamya… - Frontiers in …, 2019 - frontiersin.org
Streptococcus pneumoniae (pneumococcus, Spn) colonizes the human nasopharynx
asymptomatically but can cause infections such as otitis media, and invasive pneumococcal …

Experimental Evolution In Vivo To Identify Selective Pressures during Pneumococcal Colonization

VS Cooper, E Honsa, H Rowe, C Deitrick, AR Iverson… - Msystems, 2020 - Am Soc Microbiol
Experimental evolution is a powerful technique to understand how populations evolve from
selective pressures imparted by the surrounding environment. With the advancement of …

Inactivation of transcriptional regulator FabT influences Colony phase variation of Streptococcus pneumoniae

J Zhang, W Ye, K Wu, S Xiao, Y Zheng, Z Shu, Y Yin… - MBio, 2021 - Am Soc Microbiol
Streptococcus pneumoniae is an opportunistic pathogen that can alter its cell surface
phenotype in response to the host environment. We demonstrated that the transcriptional …

RNA cis-regulators are important for Streptococcus pneumoniae in vivo success

I Warrier, A Perry, SM Hubbell, M Eichelman… - PLoS …, 2024 - journals.plos.org
Bacteria have evolved complex transcriptional regulatory networks, as well as many diverse
regulatory strategies at the RNA level, to enable more efficient use of metabolic resources …

SP_0916 Is an Arginine Decarboxylase That Catalyzes the Synthesis of Agmatine, Which Is Critical for Capsule Biosynthesis in Streptococcus pneumoniae

MB Ayoola, MF Nakamya, LA Shack, S Park… - Frontiers in …, 2020 - frontiersin.org
The global burden of invasive pneumococcal diseases, including pneumonia and sepsis,
caused by Streptococcus pneumoniae, a Gram-positive bacterial pathogen, remains a major …

Repeated Phenotypic Evolution by Different Genetic Routes in Pseudomonas fluorescens SBW25

J Gallie, F Bertels, P Remigi… - Molecular Biology …, 2019 - academic.oup.com
Repeated evolution of functionally similar phenotypes is observed throughout the tree of life.
The extent to which the underlying genetics are conserved remains an area of considerable …

Global transcriptional responses of pneumococcus to human blood components and cerebrospinal fluid

JS Pettersen, FF Høg, FD Nielsen… - Frontiers in …, 2022 - frontiersin.org
Streptococcus pneumoniae (pneumococcus) is a leading cause of severe invasive
infectious diseases such as sepsis and meningitis. Understanding how pneumococcus …