In arbitrary dimension, in the discrete setting of finite-differences we prove a Carleman
estimate for a semi-discrete parabolic operator, in which the large parameter is connected to …

Hepatocytes form a crucially important cell layer that separates sinusoidal blood from the
canalicular bile. They have a uniquely organized polarity with a basal membrane facing liver …

Cholestatic jaundice in infancy affects approximately 1 in every 2500 term infants and is
infrequently recognized by primary providers in the setting of physiologic jaundice …

Bile was recognized by the ancient Greeks as 1 of the 4 humors; its importance is still
recognized in twenty-first century medicine, although maybe only by hepatologists. Bile …

Background Jaundice is a common symptom of inherited or acquired liver diseases or a
manifestation of diseases involving red blood cell metabolism. Recent progress has …

Progressive familial intrahepatic cholestasis (PFIC) is a group of rare disorders which are
caused by defect in bile secretion and present with intrahepatic cholestasis, usually in …

Cholestasis is a condition characterized by the abnormal production or excretion of bile, and
it can be induced by a variety of causes, the factors of which are extremely complex …

Pediatric hepatocellular carcinoma (HCC) is the second common malignant liver tumor in
children after hepatoblastoma. It differs from the adult HCC in the etiological predisposition …

Some patients with microvillus inclusion disease due to myosin 5B (MYO5B) mutations may
develop cholestasis characterized by a progressive familial intrahepatic cholestasis‐like …

Background & Aims Mutations in ABCB11 can cause deficiency of the bile salt export pump
(BSEP), leading to cholestasis and end-stage liver disease. Owing to the rarity of the …