[HTML][HTML] The neurovascular unit coming of age: a journey through neurovascular coupling in health and disease

C Iadecola - Neuron, 2017 - cell.com
The concept of the neurovascular unit (NVU), formalized at the 2001 Stroke Progress
Review Group meeting of the National Institute of Neurological Disorders and Stroke …

Emerging roles of vascular endothelium in metabolic homeostasis

X Pi, L Xie, C Patterson - Circulation Research, 2018 - Am Heart Assoc
Our understanding of the role of the vascular endothelium has evolved over the past 2
decades, with the recognition that it is a dynamically regulated organ and that it plays a …

Vascular endothelial growth factor: a neurovascular target in neurological diseases

C Lange, E Storkebaum, CR De Almodóvar… - Nature Reviews …, 2016 - nature.com
Brain function critically relies on blood vessels to supply oxygen and nutrients, to establish a
barrier for neurotoxic substances, and to clear waste products. The archetypal vascular …

Role and therapeutic potential of VEGF in the nervous system

C Ruiz de Almodovar, D Lambrechts… - Physiological …, 2009 - journals.physiology.org
The development of the nervous and vascular systems constitutes primary events in the
evolution of the animal kingdom; the former provides electrical stimuli and coordination …

[HTML][HTML] The neurovascular link in health and disease: molecular mechanisms and therapeutic implications

A Quaegebeur, C Lange, P Carmeliet - Neuron, 2011 - cell.com
At first sight, the nervous and vascular systems seem to share little in common. However,
neural and vascular cells not only are anatomically closely tied to each other, but they also …

Vascular endothelial growth factor-B in physiology and disease

M Bry, R Kivelä, VM Leppänen… - Physiological …, 2014 - journals.physiology.org
Vascular endothelial growth factor-B (VEGF-B), discovered over 15 years ago, has long
been seen as one of the more ambiguous members of the VEGF family. VEGF-B is produced …

VEGF ligands and receptors: implications in neurodevelopment and neurodegeneration

P Carmeliet, CR de Almodovar - Cellular and Molecular Life Sciences, 2013 - Springer
Intensive research in the last decade shows that the prototypic angiogenic factor vascular
endothelial growth factor (VEGF) can have direct effects in neurons and modulate processes …

Cardiomyocyte VEGFR‐1 activation by VEGF‐B induces compensatory hypertrophy and preserves cardiac function after myocardial infarction

L Zentilin, U Puligadda, V Lionetti… - The FASEB …, 2010 - Wiley Online Library
Mounting evidence indicates that the function of members of the vascular endothelial growth
factor (VEGF) family extends beyond blood vessel formation. Here, we show that the …

Mitochondrial uncoupling and longevity–A role for mitokines?

S Klaus, M Ost - Experimental gerontology, 2020 - Elsevier
Aging has been viewed both as a random process due to accumulation of molecular and
cellular damage over time and as a programmed process linked to cellular pathway …

VEGF-VEGFR system as a target for suppressing inflammation and other diseases

M Shibuya - Endocrine, Metabolic & Immune Disorders-Drug …, 2015 - ingentaconnect.com
The vascular endothelial growth factor (VEGF)-VEGF receptor (R) system is deeply involved
in angiogenesis and lymphangiogenesis. VEGFR1/Fms-like tyrosine kinase-1 (Flt-1) and …